83214-85-1

Upstream product

• 17084-13-8 potassium hexafluorophosphate 
• 14897-32-6 (triphenylphosphine)gold(I) nitrate 
• 60969-19-9 thallium(I) hexafluorophosphate 
• 14243-64-2 chlorotriphenylphosphinegold(I) 
• 14243-64-2 (triphenylphosphine)gold(I) chloride 
• 26042-63-7 silver(I) hexafluorophosphate 

Downstream Products

• 115936-52-2 platinum(methyl)2(2,2'-bipyridine)gold(PPh₃)}PF₆ 
• 1359998-79-0 [(2-(2-pyridyl)benzimidazole)Au(triphenylphosphine)][PF₆] 
• 1359998-88-1 [(triphenylphosphine)Au(μ-2-(2-pyridyl)benzimidazolato)Au(triphenylphosphine)][PF6] 

Relevant academic research and scientific papers

Cytotoxic properties of a new organometallic platinum(II) complex and its gold(i) heterobimetallic derivatives

A novel platinum(ii) organometallic complex, [Pt(pbi)(Me)(DMSO)], bearing the 2-(2′-pyridyl)-benzimidazole (pbiH) ligand, was synthesized and fully characterized. Interestingly, the reaction of this organometallic platinum(ii) complex with two distinct gold(i) phosphane compounds afforded the corresponding heterobimetallic derivatives with the pbi ligand bridging the two metal centers. The antiproliferative properties in vitro of [Pt(pbi)(Me)(DMSO)] and its gold(i) derivatives as well as those of the known coordination platinum(ii) and palladium(ii) complexes with the same ligand, of the general formula [MCl2(pbiH)], were comparatively evaluated against A2780 cancer cells, either sensitive or resistant to cisplatin. A superior biological activity of the organometallic compound clearly emerged compared to the corresponding platinum(ii) complex; the antiproliferative effects are further enhanced upon attaching the gold(i) triphenylphosphine moiety to the organometallic Pt compound. Remarkably, these novel metal species are able to overcome nearly complete resistance to cisplatin. Significant mechanistic insight into the study compounds was gained after investigating their reactions with a few representative biomolecules by electrospray mass spectrometry and X-ray crystallography. The obtained results are comprehensively discussed.

Reactivity of Ruthenium and Niobium Trihydrides with Gold Fragments. Crystal Structure of the Hexanuclear Raft Cluster

The reactions of with PF6 produce the trinuclear clusters 2>PF6 L = η-C5Me5, L' = P(C6H11)3, M = Ru

Hexaplatinum clusters with carbonyl and diphosphine ligands and the trapping of mercury(0) and thallium(I)

Hexaplatinum cluster complexes have been prepared by reduction of [PtCl2(SMe2)2] with NaBH4 in the presence of CO and the diphosphine ligands Ph2P(CH2)nPPh2, n = 2 (dp

Complexes with PtAu and PtAg bonds: Catalysis by silver(I) of alkyl exchange reactions between platinum centers

The electron-rich platinum(II) complex [PtMe2(2,2′-bpy)] (1, bpy = bipyridine) reacts with [Au(NO3)(PPh3)], [Au(BF4)(PPh3)], [Au(PF6)(PPh3)], [Ag(BF4)(PPh3)], and AgBF4 to give the Pt-M bonded complexes [PtMe2(bpy)(AuPPh3)]NO3 (3a), [PtMe2(bpy)(AuPPh3)]BF4 (3b), [PtMe2(bpy)(AuPPh3)]PF6 (3c), [PtMe2(bpy)(AgPPh3)]BF4 (3d), and [{PtMe2(bpy)}2Ag]BF4 (4), respectively. These compounds are shown to contain PtAu or PtAg bonds by their 1H, 31P, and 195Pt NMR spectroscopic properties. Complexes 3c and 4 were isolated in analytically pure form, but 3a, 3b, and 3d were too unstable thermally to characterize by elemental analysis. The Pt-Au bonded complexes appear to be the first such binuclear complexes to have been characterized unambiguously. Decomposition of the complexes occurs with formation of Ag or Au metal and equimolar amounts of Me3PtIV and MePtII derivatives. AgBF4 catalyzes the exchange of CH3 and CD3 groups between [PtMe2(bpy)] and [Pt(CD3)2(bpy)], as analyzed by MS, or between [PtMe2(1,10-phen)] (phen = phenanthroline) and [Pt(CD3)2(bpy)], as analyzed by 1H NMR.

SYNTHESIS AND STRUCTURAL CHARACTERISATION OF THE MIXED-METAL CLUSTER CATION 5-C5H4R)2(AuP(C6H5)3)2>+ WITH R = H or Si(CH3)3

Triangular "NbAu2" cluster compounds have been prepared by the reaction of 5-C5H4R)2H3> (R = H, Si(CH3)3) with gold(I) salts and the structure of 5-C5H4Si(CH3)3)2(AuP(C6H5)3)2> PF6 has been determined by X-ray diffraction.