83263-30-3Relevant academic research and scientific papers
A Facile Access to trans -3-Styryl-4-hydrazinocyclopentenes via Palladium-Catalyzed Ring Opening of Diazanorbornenes with (Z)-β-Bromostyrenes/2,3-Dibromohydrocinnamic Acids
Saranya,Chand, S. Sarath,Gopalan, Greeshma,Jijitha,Radhakrishnan
, p. 184 - 192 (2018)
trans -3-Styryl-4-hydrazinocyclopentenes have been synthesized via palladium-catalyzed desymmetrization of diazanorbornenes with (Z)-β-bromostyrenes. The reaction also works well with (Z)-β-bromostyrenes generated in situ from 2,3-dibromohydrocinnamic acids. The synthesized hydrazinocyclopentenes provide an easy route towards synthetic intermediates of many scaffolds of biological potential.
Convenient synthesis of terminal alkynes from anti-3-aryl-2,3- dibromopropanoic acids using a K2CO3/DMSO system
Cheng, Xuezhi,Jia, Jun,Kuang, Chunxiang
experimental part, p. 2350 - 2354 (2012/02/03)
A convenient, efficient, and generally applicable method was developed for the synthesis of terminal alkynes from anti-3-aryl-2,3-dibromopropanoic acids in the presence of DMSO and K2CO3.
Synthesis of (Z)-1-bromo-1-alkenes and terminal alkynes from anti-2,3-dibromoalkanoic acids by microwave-induced reaction
Kuang, Chunxiang,Yang, Qing,Senboku, Hisanori,Tokuda, Masao
, p. 4043 - 4052 (2007/10/03)
(Z)-1-Bromo-1-alkenes were stereoselectively prepared in high yields in a short reaction time by microwave irradiation of the corresponding anti-2,3-dibromoalkanoic acids in a Et3N/DMF system. A one-pot synthesis of terminal alkynes and enynes from 2,3-dibromoalkanoic acids were also developed by microwave-induced reaction.
Convenient and stereoselective synthesis of (Z)-1-bromo-1-alkenes by microwave-induced reaction
Kuang, Chunxiang,Senboku, Hisanori,Tokuda, Masao
, p. 3893 - 3896 (2007/10/03)
(Z)-1-Bromo-1-alkenes were stereoselectively prepared in high yields in a short reaction time (0.2-1.0 min) by microwave irradiation of the corresponding 2,3-dibromoalkanoic acids in DMF in the presence of triethylamine.
A mild procedure for the stereospecific transformation of trans cinnamic acid derivatives to cis β-bromostyrenes
Kim, Sun Hee,Wei, Han-Xun,Willis, Steven,Li, Guigen
, p. 4179 - 4185 (2007/10/03)
A new mild procedure has been developed for the synthesis of cis β- bromostyrene analogs with complete Z/E selectivity and good to excellent yields (58.4 - 90.9 %). The process involves carboxyl-halo-elimination of cinnamic acid dibromides by using triethylamine in N,N-dimethylformamide at room temperature. A one-pot procedure has also been described for the direct transformation of cinnamic acids to β-bromostyrenes.
Iodide-induced Debromination of Cinnamic Acid and Substituted Cinnamic Acid Dibromides in 2-Methoxyethanol
Subramanian, K.,Mathai, I. M.
, p. 909 - 911 (2007/10/02)
The second order rate constants for the iodide-induced debromination of cinnamic acid and substituted cinnamic acid dibromides in 2-methoxyethanol are reported; the reactivities follow the order: p-OCH3 > o-CH3 > p-CH3 > p-NO2 > p-Cl > m-NO2 > -H > m-CH3 > m-OCH3 > o-Cl.The m-CH3 and p-Cl derivatives have higher enthalpies and lower negative entropies of activation whereas methoxy substituted derivatives are characterised by lower enthalpies and higher negative entropies of activation than the unsubstituted acid.The free energy of activation is nearly constant.
