832714-07-5

Usage

Chemical compound

4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-[4-(methylsulfonyl)phenyl]-
Potential pharmaceutical applications

Class

Pyrazolo[3,4-d]pyrimidin-4-one derivatives
Contains a methylsulfonylphenyl group
of interest in medicinal chemistry
Potential drug candidate for treating various diseases and conditions
Molecular structure and functional groups make it promising for further research and development in pharmacology

Upstream product

• 877-66-7 4-(methylsulfonyl)phenylhydrazine 
• 64-18-6 formic acid 
• 106368-32-5 5-amino-1-<4-(methylsulfonyl)phenyl>-1H-pyrazole-4-carbonitrile 

Downstream Products

• 832716-87-7 4-[1-(4-methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1310693-20-9 C₂₃H₂₉N₅O₄S 
• 832714-08-6 4-chloro-1-[4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidine 
• 1310693-19-6 C₂₂H₂₅N₇O₃S 

Relevant academic research and scientific papers

Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control

We herein outline the design of a new series of agonists of the pancreatic and GI-expressed orphan G-protein coupled receptor GPR119, a target that has been of significant recent interest in the field of metabolism, starting from our prototypical agonist