832715-51-2

Basic information

• Product Name: Isopropyl 4-hydroxypiperidine-1-carboxylate
• Synonyms: isopropyl 4-hydroxypiperidine-1-carboxylate;4-HYDROXYPIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER;4-Hydroxy-1-piperidinecarboxylic acid 1-methylethyl ester;propyl 4-hydroxypiperidine-1-carboxylate;propan-2-yl 4-hydroxypiperidine-1-carboxylate;4-hydroxypiperidine-1-carboxylic acid iPr ester;1-Piperidinecarboxylic acid,4-hydroxy-,1-methylethyl ester
• CAS NO: 832715-51-2
• Molecular Formula: C₉H₁₇NO₃
• Molecular Weight: 187.24
• Product Categories: Organic acids
• Mol File: 832715-51-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 283.7 °C at 760 mmHg
• Flash Point: 125°C
• Appearance: /
• Density: 1.131
• Vapor Pressure: 0.000361mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.90±0.20(Predicted)
• CAS DataBase Reference: Isopropyl 4-hydroxypiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Isopropyl 4-hydroxypiperidine-1-carboxylate(832715-51-2)
• EPA Substance Registry System: Isopropyl 4-hydroxypiperidine-1-carboxylate(832715-51-2)

Safety Data

• Hazardous Substances Data: 832715-51-2(Hazardous Substances Data)

Usage

General Description

Isopropyl 4-hydroxypiperidine-1-carboxylate, also known as procaine, is a local anesthetic and a vasodilator. It is commonly used in medical procedures to reduce pain and discomfort by blocking the transmission of nerve signals. Procaine works by inhibiting the excitation of nerve cells, leading to temporary numbness in the targeted area. In addition to its anesthetic properties, it also has vasodilatory effects, meaning it can widen blood vessels, promoting increased blood flow and reducing blood pressure. It is commonly used in dentistry, ophthalmology, and dermatology, and is available in various formulations for different applications. However, it should be used cautiously, as it can cause allergic reactions and side effects when not administered properly.

InChI:InChI=1/C9H17NO3/c1-7(2)13-9(12)10-5-3-8(11)4-6-10/h7-8,11H,3-6H2,1-2H3

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 108-23-6 isopropyl chloroformate 

Downstream Products

• 897732-93-3 APD597 
• 1245140-41-3 4-(4-bromophenoxy)piperidine-1-carboxylic acid isopropyl ester 
• 1001399-58-1 1-methylethyl 4-({2-amino-7-[2-fluoro-4-(methylsulfonyl)phenyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)-1-piperidinecarboxylate 
• 1001398-41-9 (+/-)-1-methylethyl 4-({7-[2-fluoro-4-(methylsulfonyl)phenyl]-6-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)-1-piperidinecarboxylate 
• 1001399-38-7 1-methylethyl 4-({7-[2-fluoro-4-(methylthio)phenyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)-1-piperidinecarboxylate 
• 1001399-10-5 1-methylethyl 4-[(7-{4-[(dimethylamino)sulfonyl]phenyl}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-1-piperidinecarboxylate 
• 1001398-62-4 1-methylethyl 4-{[7-(4-bromo-3-fluorophenyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}-1-piperidinecarboxylate 
• 1001397-39-2 1-methylethyl 4-{[7-(4-bromo-2-fluorophenyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}-1-piperidine carboxylate 
• 1416272-94-0 C₂₃H₃₀N₄O₃S 
• 1245078-54-9 4-((R)-1-carboxyethoxy)piperidine-1-carboxylic acid isopropyl ester 
• 1001398-31-7 1-methylethyl 4-{[7-(4-bromophenyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy}-1-piperidinecarboxylate 

Relevant articles and documents

FUSED HETEROCYCLIC RING COMPOUND

A compound represented by the following formula or a salt thereof, which has an GPR119 agonist action, is useful for the prophylaxis or treatment of diabetes, obesity and the like, and shows superior efficacy: wherein P: substituted 6-membered aromatic ring, Q: (substituted) 6-membered aromatic ring, A1: CR4aR4b, NR4c, O, S, SO or SO2 {R4a-4c: H etc.}, L1: (substituted) C1-5 alkylene, L2: a bond or (substituted) C1-3 alkylene, L3-4: (substituted) C1-3 alkylene, R1: H, X, CN, (substituted) hydrocarbon, (substituted) heterocycle or (substituted) OH, or (substituted) 4- to 8-membered (heterocyclic) ring together with A1, R2: H, CN, (substituted) hydrocarbon, and R3a: -COSRA1, (substituted) 5- or 6-membered aromatic ring {RA1: (substituted) hydrocarbon or (substituted) heterocycle}.

NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO

New compounds are disclosed which have utility in the treatment of a variety of metabolic related conditions in a patient. The compounds of this invention have the structure (I): wherein X1, X2, X3, X4, Y1

PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS

Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR 119 G protein-coupled receptor modulator therapy. These novel compounds have the structure Formula I or Formula IA.