1001399-10-5

Basic information

• Product Name: 1-methylethyl 4-[(7-{4-[(dimethylamino)sulfonyl]phenyl}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-1-piperidinecarboxylate
• CAS NO: 1001399-10-5
• Molecular Weight: 489.596
• Mol File: 1001399-10-5.mol

Chemical Properties

• CAS DataBase Reference: 1-methylethyl 4-[(7-{4-[(dimethylamino)sulfonyl]phenyl}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-1-piperidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methylethyl 4-[(7-{4-[(dimethylamino)sulfonyl]phenyl}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-1-piperidinecarboxylate(1001399-10-5)
• EPA Substance Registry System: 1-methylethyl 4-[(7-{4-[(dimethylamino)sulfonyl]phenyl}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-1-piperidinecarboxylate(1001399-10-5)

Safety Data

• Hazardous Substances Data: 1001399-10-5(Hazardous Substances Data)

Upstream product

• 16019-33-3 2-(4,6-dichloropyrimidin-5-yl)acetaldehyde 
• 1001399-09-2 4-(4-chloro-5,6-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide 
• 832715-51-2 isopropyl 4-hydroxypiperidine-1-carboxylate 
• 16019-31-1 5-allyl-4,6-dichloropyrimidine 
• 16019-30-0 6-hydroxy-5-(2-propen-1-yl)-4(1H)-pyrimidinone 

Relevant articles and documents

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists

GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119

GPR119 AGONISTS FOR THE TREATMENT OF DIABETES AND RELATED DISORDERS

The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly Type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.