83287-02-9

Basic information

• Product Name: 5,6,9-trimethoxy-7H-dibenzo[de,h]quinolin-7-one
• CAS NO: 83287-02-9
• Molecular Formula: C₁₉H₁₅NO₄
• Molecular Weight: 321.3267
• Mol File: 83287-02-9.mol

Chemical Properties

• Boiling Point: 576.7°C at 760 mmHg
• Flash Point: 302.5°C
• Density: 1.315g/cm³
• Vapor Pressure: 2.68E-13mmHg at 25°C
• Refractive Index: 1.657
• CAS DataBase Reference: 5,6,9-trimethoxy-7H-dibenzo[de,h]quinolin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,9-trimethoxy-7H-dibenzo[de,h]quinolin-7-one(83287-02-9)
• EPA Substance Registry System: 5,6,9-trimethoxy-7H-dibenzo[de,h]quinolin-7-one(83287-02-9)

Safety Data

• Hazardous Substances Data: 83287-02-9(Hazardous Substances Data)

Upstream product

• 15547-67-8 6,7-dimethoxy-1-(4-methoxy-phenyl)-isoquinoline 
• 85010-25-9 8-bromo-6,7-dimethoxyisoquinoline 
• 4722-08-1 3,4-dimethoxy-β-methoxybenzeneethanamine 
• 83287-03-0 6-hydroxy-5,9-dimethoxy-7H-dibenzoquinoline-7-one 
• 74-88-4 methyl iodide 
• 100009-83-4 2,3-dihydromenisporphine 
• 83287-07-4 N-(3',4',β-trimethoxyphenethyl)-2-bromo-4-methoxybenzamide 
• 83287-05-2 2-(6,7-dimethoxy-isoquinolin-1-yl)-5-methoxybenzonitrile 
• 83287-04-1 1-(2'-carboxy-4'-methoxyphenyl)-6,7-dimethoxyisoquinoline 
• 83287-06-3 1-(2'-bromo-4'-methoxyphenyl)-6,7-dimethoxyisoquinoline 

Downstream Products

• 96681-50-4 bianfugecine 

Relevant articles and documents

Ni-Catalyzed C-H Cyanation of (Hetero)arenes with 2-Cyanoisothiazolidine 1,1-Dioxide as a Cyanation Reagent

A nickel-catalyzed C-H cyanation reaction of arenes has been developed using 2-cyanoisothiazolidine 1,1-dioxide as an electrophilic cyanation reagent. Many different directing groups can be used in this cyanation to obtain a series of cyanation products with good yields. Adopting this strategy to introduce a cyano group, natural alkaloid menisporphine was successfully synthesized through cyano group conversion that further proved the practicality of this cyanation method.

A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines

Oxoisoaporphine alkaloids are conveniently prepared via direct ring metalation of alkoxy-substituted isoquinolines at C-1, followed by reaction with iodine. Subsequent Suzuki cross-coupling of the resulting 1-iodoisoquinolines to methyl 2-(isoquinolin-1-y

Total syntheses of menisporphine and daurioxoisoporphine c enabled by photoredox-catalyzed direct C-H arylation of isoquinoline with aryldiazonium Salt

Isoquinoline alkaloids are attractive natural products due to their diverse chemical structures as well as remarkable bioactivities. Herein, we report the concise total syntheses of two isoquinoline alkaloids, menisporphine and daurioxoisoporphine C, through a mild and efficient photoredox-catalyzed direct C-H arylation of isoquinoline core with aryldiazonium salt. This new strategy is complementary to the conventional isoquinoline synthesis and would provide us a useful means to achieve a more convergent and flexible approach to access diverse isoquinoline structures.

STRUCTURE AND SYNTHESIS OF MENISPORPHINE, A NEW TYPE OF ISOQUINOLINE ALKALOID. ALKALOIDS OF MENISPERMUM DAURICUM DC. (9)

The structure of an unknown yellow base from Menispermum dauricum DC. (Menispermaceae) was determined to be 5,6,9-trimethoxy-7H-dibenzoquinolin-7-one from various spectral data and synthesis, and was named menisporphine.This is a new isoquinoline-ty