83287-04-1Relevant articles and documents
Ni-Catalyzed C-H Cyanation of (Hetero)arenes with 2-Cyanoisothiazolidine 1,1-Dioxide as a Cyanation Reagent
Ma, Junjie,Liu, Hao,He, Xin,Chen, Zhicheng,Liu, Yue,Hou, Chuanfu,Sun, Zhizhong,Chu, Wenyi
supporting information, p. 2868 - 2872 (2021/05/05)
A nickel-catalyzed C-H cyanation reaction of arenes has been developed using 2-cyanoisothiazolidine 1,1-dioxide as an electrophilic cyanation reagent. Many different directing groups can be used in this cyanation to obtain a series of cyanation products with good yields. Adopting this strategy to introduce a cyano group, natural alkaloid menisporphine was successfully synthesized through cyano group conversion that further proved the practicality of this cyanation method.
A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines
Melzer, Benedikt C.,Bracher, Franz
, p. 1564 - 1571 (2017/08/14)
Oxoisoaporphine alkaloids are conveniently prepared via direct ring metalation of alkoxy-substituted isoquinolines at C-1, followed by reaction with iodine. Subsequent Suzuki cross-coupling of the resulting 1-iodoisoquinolines to methyl 2-(isoquinolin-1-y
STRUCTURE AND SYNTHESIS OF MENISPORPHINE, A NEW TYPE OF ISOQUINOLINE ALKALOID. ALKALOIDS OF MENISPERMUM DAURICUM DC. (9)
Kunitomo, J.,Satoh, M.,Shingu, T.
, p. 3261 - 3266 (2007/10/02)
The structure of an unknown yellow base from Menispermum dauricum DC. (Menispermaceae) was determined to be 5,6,9-trimethoxy-7H-dibenzoquinolin-7-one from various spectral data and synthesis, and was named menisporphine.This is a new isoquinoline-ty