833-18-1

Basic information

• Product Name: 2-(4-FLUOROPHENYL)SUCCINIC ACID
• Synonyms: 2-(4-FLUOROPHENYL)SUCCINIC ACID;CBI-BB ZERO/006514;2-(4-fluorophenyl)butanedioic acid
• CAS NO: 833-18-1
• Molecular Formula: C₁₀H₉FO₄
• Molecular Weight: 212.17
• Mol File: 833-18-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-FLUOROPHENYL)SUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUOROPHENYL)SUCCINIC ACID(833-18-1)
• EPA Substance Registry System: 2-(4-FLUOROPHENYL)SUCCINIC ACID(833-18-1)

Safety Data

• Hazardous Substances Data: 833-18-1(Hazardous Substances Data)

Usage

Physical form

White crystalline powder

Uses

Organic synthesis, pharmaceutical research

Function

Modifies structure and function of biological molecules

Application

Building block in the synthesis of complex compounds and pharmaceuticals

Potential use

Development of new drugs and therapeutic agents

Precaution

May pose health and environmental risks if not properly managed.

Upstream product

• 109971-37-1 C₁₈H₂₄FN₃O₄ 
• 5153-69-5 4-fluoro-β-nitrostyrene 
• 405-99-2 para-fluorostyrene 
• 124-38-9 carbon dioxide 

Relevant articles and documents

Method for synthesizing succinic acid compounds

The invention provides a method for synthesizing succinic acid compounds. The method specifically comprises the following steps: adding a substrate, a photocatalyst and an alkali into a reaction tube,adding a reducing agent and a solvent under the atmosphere of CO2, conducting reacting under the irradiation of visible light, carrying out quenching treatment after the raw materials react completely, and then conducting separating and purifying to obtain a dicarboxylated product of olefin, namely a succinic acid compound. The photocatalyst is 4CzIPN or Ir[(ppy)2(dtbppy)]PF6 and the like, and the reaction substrate comprises 1,1-diaryl ethylene, a monoaryl substituted olefin compound, an acrylate compound and allene. According to the scheme provided by the invention, the reaction conditionsare mild, the applicability of the reaction substrate is wide, and the yield is basically not influenced under the condition that the reaction substrate is amplified to the gram scale; and meanwhile,the invention overcomes the defects of high toxicity of reagents and harsh reaction conditions in the prior art, and has a good industrial application prospect.

Enamines; 45. A New Simple Synthesis of 2-Phenylsuccinic Acids

A simple route to 2-phenylsuccinic acids consists of the reaction of 1,1-dimorpholinoethene with β-nitrostyrenes at room temperature and hydrolysis of the 1:1 adduct thus obtained with hydrochloric acid.The method affords good overall yields of 2-phenylsuccinic acids.