83301-06-8Relevant academic research and scientific papers
Novel solid-state synthesis of polyfunctionalized 3,9-diazatetraasteranes
Hilgeroth, Andreas,Baumeister, Ute,Heinemann, Frank W.
, p. 1213 - 1218 (2007/10/03)
Upon irradiation, crystalline 4-methoxyphenyl-1,4-dihydropyridines 1 undergo nearly quantitative [2+2]cycloaddition to form, via the ring-open intermediates 2, the centrosymmctric, polyfunctionalized 3,9-diazatetraasteranes 3. The centrosymmetric character of 3 was confirmed by 1H NMR spectral data as well as by X-ray crystal structure analysis. The dimerization reactions prove to be topochemically controlled by the nearest distance between potentially reacting double bonds, as well as by the conformationally determined packing restraints. This latter factor is shown by the X-ray crystal structure analysis of one dimerizing and one photostable derivative of the monomers 1.
Novel solid-state synthesis of dimeric 4-aryl-1,4-dihydropyridines
Hilgeroth, Andreas,Heinemann, Frank W.
, p. 359 - 364 (2007/10/03)
On irradiation in the solid state the 4-aryl-1,4-dihydroypridines 1 undergo [2+2] cycloadditon to centro-symmetric head-to-tail dimers 3 and 4a. The almost exclusive formation of the cage dimers 3 via the C2-symmetric syn-dimers 2 takes place in nearly quantitative yields, in contrast with the cycloaddition reaction of the anti-dimer 4a, which is accomplished by photooxidation to pyridine 5a.
1,2,3,4-TETRAHYDROPYRIMIDINES AND SOME OTHER COMPOUNDS BASED ON PROPIOLIC ACID DERIVATIVES
Khanina, E. L.,Mutsenietse, D. Kh.,Dubur, G. Ya.
, p. 431 - 433 (2007/10/02)
The reactions of ethyl propiolate and propiolamide with methylene and benzaldehyde and anisaldehyde in an acidic medium, in which the corresponding 2-oxo-1,2,3,4-tetrahydropyrimidines and 1,4-dihydropyrimidines or a 3,4-dihydropyrimidine derivative are formed, were studied.
SYNTHESIS AND PROPERTIES OF 1-SUBSTITUTED DERIVATIVES OF DIETHYL 4-ARYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS
Lusis, V. K.,Dubur, G. Ya.
, p. 813 - 818 (2007/10/02)
1-Unsubstituted 4-aryl-3,5-diethoxycarbonyl-1,4-dihydropyridines in the presence of NaH form anions that react with alkyl halides, acid chlorides, and halo acid esters to form the corresponding 1-substituted derivatives of 1,4-dihydropyridine.Hydrolysis o
