83304-64-7

Upstream product

• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 83304-60-3 benzyl (2,4-dimethoxybenzyl)-amine 
• 83304-61-4 diethyl(N-benzyl)-N-(2,4-dimethoxy-benzyl)-amino-malonate 
• 96724-73-1 N-benzyl-1-(2,4-dimethoxyphenyl)methanamine 
• 81902-49-0 diethyl N-(2,4-dimethoxybenzyl)-amino-malonate 
• 83304-63-6 1-(2,4-Dimethoxy-benzyl)-3-hydroxy-3-methyl-5-oxo-pyrrolidine-2,2-dicarboxylic acid diethyl ester 

Downstream Products

• 85621-90-5 (3R,4R)-1-(2,4-Dimethoxy-benzyl)-4-iodomethyl-3-(2-methyl-[1,3]dioxolan-2-yl)-azetidin-2-one 
• 85621-88-1 Methanesulfonic acid (2S,3S)-1-(2,4-dimethoxy-benzyl)-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-ylmethyl ester 
• 96724-95-7 (2S,3S)-1-(2,4-Dimethoxy-benzyl)-2-hydroxymethyl-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 85621-87-0 (3R,4R)-1-(2,4-Dimethoxy-benzyl)-4-hydroxymethyl-3-(2-methyl-[1,3]dioxolan-2-yl)-azetidin-2-one 
• 87231-35-4 [(2S,3R)-1-(2,4-Dimethoxy-benzyl)-3-(2-methyl-[1,3]dioxolan-2-yl)-4-oxo-azetidin-2-yl]-acetonitrile 
• 87542-16-3 (2RS,3RS)-1-(2,4-dimethoxybenzyl)-3-(2-methyl-1,3-dioxolan-2-yl)-4-oxoazetidine-2-carboxylic acid 
• 85621-92-7 trans ethyl 1-(2,4-dimethoxybenzyl)-3-(2-methyl-1,3-dioxolan-2-yl)-4-oxoazetidinecarboxylate 
• 85621-92-7 Ethyl (2RS,3SR)-1-(2,4-Dimethoxybenzyl)-3-(2-methyl-1,3-dioxolan-2-yl)-4-oxoazetidine-2-carboxylate 
• 85621-94-9 Diethyl-1-(2,4-dimethoxybenzyl)-3-(2-methyl-1,3-dioxolane-2-yl)-4-oxo-2,2-azetidine-dicarboxylate 

Relevant academic research and scientific papers

SIMPLE AND CONDENSED β-LACTAMS-I. THE APPLICATION OF DIKETENE IN β-LACTAM SYNTHESIS. THE SYNTHESIS AND FUNCTIONAL GROUP MANIPULATIONS OF DIETHYL 3-ACETYL-4-OXOAZETIDINE-2,2-DICARBOXYLATES

Acetylation of the N-substituted diethyl aminomalonates 3a-3d with diketene furnished the ring tautomers 6a-6d of the expected acetoacetyl derivatives 5.By treatment with iodine and sodium ethoxide compounds 6a-6d are smoothly converted into the β-lactam

Azetidinone-4-carboxylate containing a protected 3-acetyl group and process for their preparation

The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particularly, the invention concerns new compounds of the Formula (V) STR1 wherein R is a group suitable for the protection of amides; Z is alkyl; and Y1

Beta-lactam compounds containing a C-acetal group and process for their preparation

The invention relates to new heterocyclic compounds containing a C-acetyl group and a process for their preparation. More particularly, the invention concerns new compounds of the formula (III). STR1 in which R is a protecting group suitable for temporary

Beta-lactam compounds containing a protected C-acetyl group, process for their preparation and pharmaceutical compositions containing them

The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particulary, the invention concerns new compounds of the formula (VI) STR1 wherein R1 is hydrogen or a group suitable for a temporary protection or amides, X is hydroxyl, halogen, cyano or an --O--SO2 --R2 group, in which R2 is lower alkyl or aryl, Y1 and Y2 together form a group suitable for a temporary protection of a keto group. The new compounds possess anaphylactic properties and are valuable intermediates of thienamycin synthesis. Their preparation and the new intermediates obtained during their preparation are also within the scope of the invention.