83326-44-7

Upstream product

• 6296-89-5 [4-(methoxycarbonyl)phenyl]hydrazine hydrochloride 
• 108-24-7 acetic anhydride 
• 619-45-4 4-methoxycarbonyl aniline 
• 64-19-7 acetic acid 
• 4510-12-7 methyl 4-hydrazinobenzoate 
• 72754-78-0 4-(2,5-Dimethyl-3-oxo-2,3-dihydro-furan-2-ylazo)-benzoic acid methyl ester 

Downstream Products

• 867348-75-2 methyl 4-(2-acetyl-2-methylhydrazino)benzoate 
• 681860-27-5 methyl 4-(2-acetyl-1,2-dimethylhydrazino)benzoate 

Relevant academic research and scientific papers

Indole synthesis by rhodium(III)-catalyzed hydrazine-directed C-H activation: Redox-neutral and traceless by N-N bond cleavage

Fishing for complements! There is an alternative to the useful Fischer indole synthesis. The new method utilizes the same retrosynthetic disconnection but is based on a RhIII-catalyzed directed C-H activation step and a successive coupling with alkynes. Copyright

6-Heteroarylpyridoindolone Derivatives, Their Preparation and Therapeutic Use Thereof

The disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing the same and therapeutic use thereof.

6-Substituted pyridoindolone derivatives, production and therapeutic use thereof

Compounds of formula: and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1, R2, R3, R4, and R5, have the meanings given in the description; pharmaceutical compositions comprising said compounds; and processes for preparing said compounds and methods of use thereof.

REACTION OF 2-ARYLAZO-2,5-DIMETHYL-3(2H)-FURANONES WITH AMMONIA. PREPARATION OF β-ACETYL-β-(3-AMINO-2-BUTENOYL)ARYLHYDRAZINES.

Ring opening of 2-arylazo-2,5-dimethyl-3(2H)-furanones (1a-d) with ammonia leads to previously unknown β-acetyl-β-(3-amino-2-butenoyl)arylhydrazines (3a-d).The reaction mechanism is discussed.