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2,4,6-Trimethoxy-5-nitropyrimidine is an organic compound with the chemical formula C8H8N4O5. It is a derivative of pyrimidine, a heterocyclic organic compound, featuring three methoxy groups and a nitro group attached to the pyrimidine ring. This yellowish crystalline powder is soluble in organic solvents such as acetone, ethyl acetate, and dichloromethane.

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  • 83356-02-9 Structure
  • Basic information

    1. Product Name: 2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE
    2. Synonyms: 2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE
    3. CAS NO:83356-02-9
    4. Molecular Formula: C7H9N3O5
    5. Molecular Weight: 215.16
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 83356-02-9.mol
    9. Article Data: 3
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 407.959 °C at 760 mmHg
    3. Flash Point: 200.527 °C
    4. Appearance: /
    5. Density: 1.347 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.526
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE(83356-02-9)
    12. EPA Substance Registry System: 2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE(83356-02-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 83356-02-9(Hazardous Substances Data)

83356-02-9 Usage

Uses

Used in Pharmaceutical Synthesis:
2,4,6-Trimethoxy-5-nitropyrimidine serves as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of various medicinal compounds.
Used in Agrochemical Production:
2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE is also utilized as an intermediate in the production of agrochemicals, contributing to the creation of substances that help protect and enhance crop yields.
Used in Materials Science:
2,4,6-Trimethoxy-5-nitropyrimidine has potential applications in the field of materials science, where its unique properties can be employed to develop new materials with specific characteristics.
Used in Organic Electronics:
2,4,6-TRIMETHOXY-5-NITROPYRIMIDINE also holds promise in the realm of organic electronics, where it may be used to create novel electronic devices and components with improved performance.

Check Digit Verification of cas no

The CAS Registry Mumber 83356-02-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,3,5 and 6 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83356-02:
(7*8)+(6*3)+(5*3)+(4*5)+(3*6)+(2*0)+(1*2)=129
129 % 10 = 9
So 83356-02-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H9N3O5/c1-13-5-4(10(11)12)6(14-2)9-7(8-5)15-3/h1-3H3

83356-02-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4,6-Trimethoxy-5-nitropyrimidine

1.2 Other means of identification

Product number -
Other names 5-nitro-2,4,6-trimethoxypyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83356-02-9 SDS

83356-02-9Relevant articles and documents

Sigma Complexes in the Pyrimidine Series. 5. Reaction of 5-Nitromethoxypyrimidines with the Anion of Malonic Acid Dinitrile

Cherkasov, V. M.,Remennikov, G. Ya.,Kisilenko, A. A.

, p. 526 - 529 (1982)

The reaction of 5-nitromethoxypyrimidines with malonic acid dinitrile in the presence of potassium hydroxide was studied.It is shown that attack by the nucleophile is realized only in the positions of the pyrimidine ring occupied by methoxy groups and tha

1,2,3',5'-TETRAHYDRO-2'H-SPIRO[INDOLE-3,1'-PYRROLO[3,4-C]PYRROLE]-2,3'-DIONE COMPOUNDS AS THERAPEUTIC AGENTS ACTIVATING TP53

-

, (2019/07/24)

The invention relates to 1,2,3',5'-tetrahydro-2'H-spiro[indole-3,1'-pyrrolo[3,4-c]pyrrole]-2,3'-dione compounds represented by formula (I), wherein all symbols and variables are as defined in the description. The compounds can find use in a method of prevention and/or treatment of diseases selected from the group consisting of cancer, immune diseases, inflammatory conditions, allergic skin diseases associated with excessive proliferation, blinding disease and viral infections.

Electrophilic tetraalkylammonium nitrate nitration. II. Improved anhydrous aromatic and heteroaromatic mononitration with tetramethylammonium nitrate and triflic anhydride, including selected microwave examples

Shackelford, Scott A.,Anderson, Mark B.,Christie, Lance C.,Goetzen, Thomas,Guzman, Mark C.,Hananel, Martha A.,Kornreich, Wayne D.,Li, Haitao,Pathak, Ved P.,Rabinovich, Alex K.,Rajapakse, Ranjan J.,Truesdale, Larry K.,Tsank, Stella M.,Vazir, Haresh N.

, p. 267 - 275 (2007/10/03)

A new one-pot nitration employing tetramethylammonium nitrate and trifluoromethanesulfonic anhydride in dichloromethane to provide a ready source of the nitronium triflate nitrating agent is presented. Rapid and selective nitration with a variety of aromatic and heteroaromatic substrates is achieved resulting in the synthesis of several novel organic compounds. A distinct advantage is the removal of undesired byproducts by aqueous workup. This very mild nitration permits large-scale syntheses and gives high isolated product yields that often require no further purification. This tetramethylammonium nitrate-based nitration also has been applied to microwave-assisted conditions, and the results with several compounds are outlined.

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