13106-85-9 Usage
Description
2,4,6-Trimethoxypyrimidine is a pyrimidine derivative known for its role in chemical studies and reactions. It is synthesized through the reaction of 2,4,6-trichloropyrimidine with sodium ethoxide at 70-100°C and can be transformed into 1,6-dihydro-2,4-dimethoxy-1-methyl-6-oxopyrimidine by the Hilbert-Johnson reaction.
Uses
Used in Chemical Research:
2,4,6-Trimethoxypyrimidine is used as a model compound in the study of qualitative composition of mixtures formed during the methylation of barbituric acid and its derivatives by diazomethane. This application is significant for understanding the chemical reactions and interactions involved in the process, contributing to the broader field of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 13106-85-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,0 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13106-85:
(7*1)+(6*3)+(5*1)+(4*0)+(3*6)+(2*8)+(1*5)=69
69 % 10 = 9
So 13106-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O3/c1-10-5-4-6(11-2)9-7(8-5)12-3/h4H,1-3H3
13106-85-9Relevant articles and documents
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Neville
, p. 1253 (1972)
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Fisher,Johnson
, p. 727,731 (1932)
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REACTION OF BARBITURIC ACID AND ITS METHYL DERIVATIVES WITH DIAZOMETHAN IN ETHERS
Krasnov, K. A.,Slesareva, V. I.,Studentsov, E. P.,Slesarev, V. I.
, p. 1765 - 1769 (2007/10/02)
A full scheme for the methylation of barbituric acid with diazomethane in diethyl ether, glyme, and THF was formulated.For barbituric acid and its N-methyl derivatives the reaction takes place at the oxygen atoms of the β-dicarbonyl fragment.The 6-methoxyuracil and its derivatives which are formed here are subsequently methylated at the nitrogen and oxygen atoms.The reaction takes place in accordance with the structures of the monoanions of the compounds being methylated.
