83393-47-9

Basic information

• Product Name: Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI)
• Synonyms: Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI);Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-;2-Chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1-ethanone;3-(Chloroacetyl)-1H-pyrrolo[2,3-b]pyridine, 2-Chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one;2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone
• CAS NO: 83393-47-9
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.61768
• Product Categories: ACETYLHALIDE
• Mol File: 83393-47-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.41 g/cm³
• Refractive Index: 1.669
• CAS DataBase Reference: Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI)(83393-47-9)
• EPA Substance Registry System: Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI)(83393-47-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 83393-47-9(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI) is a chemical compound with the molecular formula C9H6ClN2O. It is a pyrrolopyridine derivative that is commonly used in pharmaceutical research as a building block for the synthesis of various bioactive molecules. Ethanone, 2-chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI) is of interest due to its potential medicinal properties and is being studied for its potential applications in the treatment of various diseases. Its unique structure and properties make it a valuable tool for drug discovery and development. Further research is being conducted to explore its potential therapeutic uses and applications in the pharmaceutical industry.

InChI:InChI=1/C9H7ClN2O/c10-4-8(13)7-5-12-9-6(7)2-1-3-11-9/h1-3,5H,4H2,(H,11,12)

Upstream product

• 271-63-6 7-Azaindole 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 4649-12-1 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-ethylamine 
• 1134099-83-4 2-(4-benzylpiperidin-1-yl)-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone 

Relevant articles and documents

INHIBITORS OF DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1B

The present invention relates to compounds of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof (I), in particular for use in the treatment, amelioration or prevention of cancer, Alzheimer, Parkinson, Down syndrome, Metabolic syndrome, Diabetes and/or osteoarthritis.

Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors

From four molecules, inspired by the structural features of fascaplysin, with an interesting potential to inhibit cyclin-dependent kinases (CDKs), we designed a new series of tri-heterocyclic derivatives based on 1H-pyrrolo[2,3-b]pyridine (7-azaindole) an

PYRIDINONYL PDK1 INHIBITORS

The present invention provides pyridinonyl PDKl inhibitors and methods of treating cancer using the same.