83402-87-3

Basic information

• Product Name: 2-Oxo-4-phenylbutyric acid methyl ester
• Synonyms: Methyl 2-oxo-4-phenylbutanoic acid;Methyl 2-oxo-4-phenylbutanoate
• CAS NO: 83402-87-3
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.22
• Mol File: 83402-87-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 299.1°C at 760 mmHg
• Flash Point: 133.3°C
• Appearance: /
• Density: 1.115g/cm³
• Vapor Pressure: 0.00121mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: 2-Oxo-4-phenylbutyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxo-4-phenylbutyric acid methyl ester(83402-87-3)
• EPA Substance Registry System: 2-Oxo-4-phenylbutyric acid methyl ester(83402-87-3)

Safety Data

• Hazard Codes: F
• Hazardous Substances Data: 83402-87-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H12O3/c1-14-11(13)10(12)8-7-9-5-3-2-4-6-9/h2-6H,7-8H2,1H3

Upstream product

• 553-90-2 Dimethyl oxalate 
• 103-63-9 1-phenyl-2-bromoethane 
• 3277-89-2 phenethylmagnesium bromide 
• 1025483-29-7 methyl 2-cyano-4-phenylbutanoate 
• 64920-29-2 2-oxo-4-phenylbutanoic acid ethyl ester 
• 7226-82-6 (RS)-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 125783-17-7 3-phenyl-cyclobutane-1,2-dione 
• 67-56-1 methanol 
• 710-11-2 2-oxo-4-phenylbutyric acid 
• 186581-53-3 diazomethane 

Downstream Products

• 83402-88-4 propyl 2-oxo-4-phenylbutyrate 
• 710-11-2 2-oxo-4-phenylbutyric acid 
• 7226-82-6 (RS)-2-hydroxy-4-phenylbutanoic acid methyl ester 
• 1010804-80-4 (2R)-(-)-methyl 2-hydroxy-2-methyl-4-phenylbutanoate 
• 1043605-55-5 (2S)-(+)-methyl 2-hydroxy-2-methyl-4-phenylbutanoate 
• 1433958-95-2 C₁₈H₂₀O₄ 
• 1433958-97-4 C₁₈H₂₀O₄ 
• 1334164-13-4 C₂₁H₃₀N₂O₇ 

Relevant articles and documents

Synthesis and biological evaluation of truncated derivatives of abyssomicin C as antibacterial agents

The synthesis and antibacterial activity of two new highly truncated derivatives of the natural product abyssomicin C are reported. This work outlines the limits of structural truncation of the natural product and consequently provides insights for furthe

A 3 - glyceraldehyde phosphate dehydrogenase inhibitor and its preparation method and application

The invention provides an inhibitor of glyceraldehyde-3-phosphate dehydrogenase, a preparation method and anticancer application thereof. According to the invention, pharmacological experiments show that the compound has strong killing effect on human col

Construction of 1,2,5-tricarbonyl compounds using methyl cyanoacetate as a glyoxylate anion synthon combined with copper(I) iodide-catalyzed aerobic oxidation

A practical and efficient synthesis of various 1,2,5-tricarbonyl compounds is described. The synthesis has been carried out by a conjugate addition of methyl cyanoacetate to the β-position of α,β-unsaturated carbonyl compounds and a subsequent copper(I) iodide-catalyzed aerobic oxidation. In addition, various α-aryl- and α-alkyl-α-keto esters have been synthesized using a similar approach. Copyright