834898-11-2Relevant articles and documents
Practical and efficient enantioselective synthesis of α-amino acids in aqueous media
Suarez, Rosa M.,Sestelo, Jose Perez,Sarandeses, Luis A.
, p. 3584 - 3587 (2004)
Enantiomerically pure natural and unnatural α-amino acids have been synthesized from a chiral melhyleneoxazolidinone by means of a highly diastereoselective 1,4-conjugate addition of alkyl iodides in aqueous media. The zinc-copper conjugate addition reaction exhibits high chemoselectivity, with the possibility of using functionalized iodides, to afford a single diastereomer in short reaction times and with good yields.