834918-60-4Relevant academic research and scientific papers
One-pot synthesis of aryl phosphoramidate derivatives of AZT/d4T as anti-HIV prodrugs
Jiang, Peng,Guo, Xin,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
, p. 2537 - 2539 (2005)
Arbuzov reaction of aryl phosphorodichloridite with mixture of one equivalent of AZT or d4T and one equivalent of tert-butyl alcohol led to the corresponding AZT/d4T aryl H-phosphonate diesters, and the following reaction of the H-phosphonate diesters wit
New and efficient approach to aryl phosphoramidate derivatives of AZT/d4T as anti-HIV prodrugs
Li, Xueshu,Fu, Hua,Jiang, Yuyang,Zhao, Yufen,Liu, Jinyong
, p. 2600 - 2602 (2007/10/03)
Ester exchange of diaryl phosphite with AZT or d4T produced aryl AZT/d4T H-phosphonate, and the following reaction with amino acid esters in the presence of hexachloroethane and triethylamine yielded membrane-soluble anti-HIV prodrugs aryl phosphoramide d
