173070-83-2

Basic information

• Product Name: L-Alanine,N-(2',3'-didehydro-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester
• Synonyms: So 324
• CAS NO: 173070-83-2
• Molecular Formula: C20H24 N3 O8 P
• Molecular Weight: 465.4
• Mol File: 173070-83-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Alanine,N-(2',3'-didehydro-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine,N-(2',3'-didehydro-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester(173070-83-2)
• EPA Substance Registry System: L-Alanine,N-(2',3'-didehydro-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester(173070-83-2)

Safety Data

• Hazardous Substances Data: 173070-83-2(Hazardous Substances Data)

Upstream product

• 3056-17-5 stavudin 
• 3426-89-9 phenyl phosphorodichloridite 
• 10065-72-2 L-Alanine methyl ester 
• 834918-60-4 C₁₆H₁₇N₂O₆P 
• 142629-80-9 phenyl methoxyalaninyl phosphorochloridate 

Downstream Products

• 3056-17-5 stavudin 
• 108-95-2 phenol 
• 180076-92-0 alaninyl-d4T-monophosphate 

Relevant articles and documents

Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite

New phosphate derivatives of the anti-HIV nucleoside analogue d4T were prepared as potential membrane-soluble prodrugs of the bioactive free nucleotide. The enhanced antiviral potency and/or reduced cytotoxicity of the derivatives leads to an increase in

One-pot synthesis of aryl phosphoramidate derivatives of AZT/d4T as anti-HIV prodrugs

Arbuzov reaction of aryl phosphorodichloridite with mixture of one equivalent of AZT or d4T and one equivalent of tert-butyl alcohol led to the corresponding AZT/d4T aryl H-phosphonate diesters, and the following reaction of the H-phosphonate diesters wit