83528-19-2

Upstream product

• 83528-08-9 methyl 2-(2-chloro-4-nitrobenzene)propionate 
• 83528-10-3 2-(2-Chloro-4-nitro-phenyl)-propionic acid 
• 88975-09-1 2-(2-Chloro-4-nitro-phenyl)-2-methyl-malonic acid diethyl ester 
• 99-54-7 3,4-dichloronitrobenzene 

Downstream Products

• 83528-37-4 2-[2-Chloro-4-(pyridin-2-ylamino)-phenyl]-propionic acid 

Relevant academic research and scientific papers

Nonsteroidal antiinflammatory agents. 2. [(Heteroarylamino)phenyl]alkanoic acids

A series of [(heteroarylamino)phenyl]alkanoic acids pyridine, quinoline, or pyrimidine as the heteroaryl moiety was prepared as potential antiinflammatory agents. Among them, 2-[4-(2-pyridylamino)phenyl]propionic acid (14b) showed excellent antiinflammatory and analgesic activities with less tendency to cause gastric side effects. Structure-activity relationships are discussed.