83540-94-7

Basic information

• Product Name: (R)-2-Hydroxysuccinic Acid Methyl Ester
• Synonyms: (R)-2-Hydroxysuccinic Acid Methyl Ester;(R)-3-Hydroxy-4-methoxy-4-oxobutanoic acid
• CAS NO: 83540-94-7
• Molecular Formula: C₅H₈O₅
• Molecular Weight: 148.11402
• Product Categories: Aliphatics;Chiral Reagents;Miscellaneous Reagents
• Mol File: 83540-94-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318°C at 760 mmHg
• Flash Point: 138.7°C
• Appearance: /
• Density: 1.383g/cm³
• Vapor Pressure: 3.08E-05mmHg at 25°C
• Refractive Index: 1.473
• PKA: 4.03±0.19(Predicted)
• CAS DataBase Reference: (R)-2-Hydroxysuccinic Acid Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Hydroxysuccinic Acid Methyl Ester(83540-94-7)
• EPA Substance Registry System: (R)-2-Hydroxysuccinic Acid Methyl Ester(83540-94-7)

Safety Data

• Hazardous Substances Data: 83540-94-7(Hazardous Substances Data)

Usage

Uses

(R)-2-Hydroxysuccinic Acid Methyl Ester is used in the preparation of their use in treating cancer or amyloidosis.

InChI:InChI=1/C5H8O5/c1-10-5(9)3(6)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)/t3-/m1/s1

Upstream product

• 67-56-1 methanol 
• 636-61-3 D-Malic acid 
• 3966-55-0 (R)-methoxy-succinic acid 
• 83541-02-0 (R)-2,5-dioxotetrahydrofuran-3-yl 2,2,2-trifluoroacetate 

Downstream Products

• 205382-87-2 methyl (5S)-2-oxo-1,3-oxazolidine-5-carboxylate 
• 307532-01-0 (R)-methyl 4-(tert-butyldimethylsilyloxy)-2-hydroxybutanoate 
• 1350543-83-7 methyl (2R)-2,4-O-benzylidene-2,4-dihydroxybutanoate 
• 70681-41-3 (R)-dimethyl malate 
• 676347-30-1 3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2-[(R)-2-((R)-3-hydroxy-3-methoxycarbonyl-propionylamino)-2-(3-methyl-[1,2,4]oxadiazol-5-yl)-ethylsulfanylmethyl]-5-methoxy-6-methyl-benzoic acid 
• 676347-29-8 allyl 3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-((R)-3-hydroxy-3-(methoxycarbonyl)-propionylamino)-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoate 

Relevant articles and documents

Structural and Functional Analysis of Bacterial Sulfonosphingolipids and Rosette-Inducing Factor 2 (RIF-2) by Mass Spectrometry-Guided Isolation and Total Synthesis

We have analyzed the abundance of bacterial sulfonosphingolipids, including rosette-inducing factors (RIFs), in seven bacterial prey strains by using high-resolution tandem mass spectrometry (HRMS2) and molecular networking (MN) within the Glob

ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans a

Direct, catalytic synthesis of carbapenams via cycloaddition/rearrangement cascade reaction: Unexpected acetylenes' structure effect

Reactions of acetylenes derived from glyceraldehyde and propargyl aldehyde show remarkable reactivity in Kinugasa cycloaddition/rearrangement cascade process catalyzed by Cu(I) ion. Reactions proceed by formation of a rigid dinuclear copper(I) complex in which each copper ion is coordinated to one or both oxygen atoms in the acetylene molecule and to both triple bonds. It has been demonstrated that one oxygen atom can be replaced by the phenyl ring, which is able to coordinate the copper ion by the aromatic sextet. Kinugasa reactions that proceed in a high yield can also be performed in the presence of a catalytic amount of the copper salt to provide products in an acceptable yield without a decrease of diastereoselectivity.