83548-60-1

Usage

InChI:InChI=1/C14H11ClN2S/c1-8-9(2)18-14-11(8)12(15)16-13(17-14)10-6-4-3-5-7-10/h3-7H,1-2H3

Upstream product

• 2227-79-4 benzenecarbothioamide 
• 100-47-0 benzonitrile 
• 4815-24-1 2-amino-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester 

Downstream Products

• 83548-67-8 (5,6-Dimethyl-2-phenyl-thieno[2,3-d]pyrimidin-4-yl)-hydrazine 
• 1611471-56-7 5,6-dimethyl-4-morpholin-4-yl-2-phenylthieno[2,3-d]pyrimidine 
• 83548-75-8 8,9-Dimethyl-5-phenyl-tetrazolo[1,5-c]thieno[3,2-e]pyrimidine 
• 401511-12-4 2-phenyl-4-[(2-hydroxy)ethyl]amino-5,6-dimethylthieno[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold

A series of novel thienopyrimidin-4-amines have been synthesized and evaluated as phosphodiesterase (PDE) inhibitors. A rationale for the observed selectivity against PDE7 has been obtained from molecular modelling studies on the most active compounds. This journal is the Partner Organisations 2014.

Microwave-Assisted Synthesis of Novel 5-Substituted-2,3-dihydroimidazo[1,2-c]thieno[3,2-e]pyrimidines

A novel, facile microwave-assisted route for the synthesis of imidazo[1,2-c]thieno[3,2-e]pyrimidines 4 in quantitative yields is reported. The intermediates 4-chlorothieno[2,3-d]pyrimidines 3 were synthesized under one-pot reaction conditions.

Synthesis and Biological Activity of Tetrazolothienopyrimidines

4-Hydrazinothienopyrimidines (VI) undergo cyclization with nitrous acid to give tetrazolothienopyrimidines (VII).The latter compounds have been screened for their analgesic and antiinflammatory activities.