83558-08-1

Basic information

• Product Name: 1-(4-bromophenyl)-6, 6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
• Synonyms: 1-(4-bromophenyl)-6, 6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
• CAS NO: 83558-08-1
• Molecular Weight: 394.311
• Mol File: 83558-08-1.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-bromophenyl)-6, 6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-6, 6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one(83558-08-1)
• EPA Substance Registry System: 1-(4-bromophenyl)-6, 6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one(83558-08-1)

Safety Data

• Hazardous Substances Data: 83558-08-1(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 70-11-1 α-bromoacetophenone 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 87324-32-1 1-(4-Bromo-phenyl)-7,7-dimethyl-2-phenyl-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one 
• 87324-21-8 1-(4-Bromo-phenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-indol-4-one oxime 

Relevant articles and documents

A metal-free visible light promoted three-component facile synthesis of 4-oxo-tetrahydroindoles in ethanol–water

A mild and efficient visible light–mediated one-pot multicomponent tandem approach to construct 4-oxo-tetrahydroindoles in ethanol–water medium at room temperature has been described. The characteristics of reported methodology are the utilization of visi

In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest

Prompted by the in silico docking study predictions the first β-cyclodextrin (β-CD) mediated synthesis of 4-oxo-4,5,6,7-tetrahydroindoles in water was achieved via a 3-component reaction under neutral conditions. A range of compounds was prepared by using

Sulfamic acid promoted one-pot multicomponent reaction: A facile synthesis of 4-oxo-tetrahydroindoles under ball milling conditions

We report an efficient and facile one-pot synthesis of 4-oxo-tetrahydroindoles using sulfamic acid under ball milling conditions. The present protocol for preparation of biologically important 4-oxo-tetrahydroindoles offers several advantages such as mild

Wang resin-supported sulfonic acid-catalyzed multicomponent reaction in water leading to 4-oxo-4,5,6,7-tetrahydroindole derivatives

A greener approach for the synthesis of 4-oxo-4,5,6,7-tetrahydro indole derivatives has been achieved through Wang-OSO3H-mediated three-component reaction involving dimedone, phenacyl bromide, and primary amine in water. A variety of indole der

Synthesis and Mass Spectrometry of 4-Oxo-4,5,6,7-tetrahydroindole and 4-Oxo-4,5,6,7-tetrahydrobenzofuran Derivatives

We describe in this communication the synthesis and mass spectrometry of some 1-aryl-2-phenyl-4-oxo-4,5,6,7-tetrahydroindole (IIIb, IVab-VIIab,VIIIb, IXb) and 2-phenyl-4-oxo-4,5,6,7-tetrahydrobenzofuran derivatives (IIab).The fragmentations of these compo