83568-11-0

Basic information

• Product Name: 2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester
• Synonyms: 2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester;ethyl 3,4-dihydro-2H-pyran-2-carboxylate
• CAS NO: 83568-11-0
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.18
• Mol File: 83568-11-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 214.1°C at 760 mmHg
• Flash Point: 81.3°C
• Appearance: /
• Density: 1.077g/cm³
• Vapor Pressure: 0.159mmHg at 25°C
• Refractive Index: 1.462
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly)
• CAS DataBase Reference: 2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester(83568-11-0)
• EPA Substance Registry System: 2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester(83568-11-0)

Safety Data

• Hazardous Substances Data: 83568-11-0(Hazardous Substances Data)

Usage

General Description

2H-Pyran-2-carboxylic acid, 3,4-dihydro-, ethyl ester is a chemical compound with the molecular formula C8H10O3. It is an ethyl ester of 2H-pyran-2-carboxylic acid, which is a heterocyclic compound with a pyran ring. This chemical is often used in pharmaceutical and agricultural products, as well as in the production of fragrances and flavoring additives. It is a colorless liquid with a fruity odor, and it is known for its use as an intermediate in the synthesis of various organic compounds. Additionally, it is important to handle this chemical with care, as it may cause irritation to the skin, eyes, and respiratory system, and it should be stored in a cool, dry place away from heat and direct sunlight.

InChI:InChI=1/C8H12O3/c1-2-10-8(9)7-5-3-4-6-11-7/h4,6-7H,2-3,5H2,1H3

Upstream product

• 16698-52-5 3,4-dihydro-2H-pyran-2-carboxylic acid sodium salt 
• 75-03-6 ethyl iodide 
• 110811-34-2 ethyl tetrahydro-2H-pyran-2-carboxylate 
• 34201-01-9 3,4-dihydro-2H-pyran-2-carboxylic acid 
• 100-73-2 acrolein dimer 

Downstream Products

• 49831-28-9 3,4-Dihydro-2H-pyran-carbonsaeure-(2)-amid 
• 3749-36-8 2-hydroxymethyl-3,4-dihydro-2H-pyran 
• 5257-20-5 7-Oxo-6,8-dioxabicyclo<3.2.1>octane 

Relevant articles and documents

Manganese-Catalyzed Desaturation of N-Acyl Amines and Ethers

Enamines and enol ethers are versatile synthons for chemical synthesis. While several methods have been developed to access such molecules, prefunctionalized starting materials are usually required, and direct desaturation methods remain rare. Herein, we report direct desaturation reactions of N-protected cyclic amines and cyclic ethers using a mild I(III) oxidant, PhI(OAc)2, and an electron-deficient manganese pentafluorophenylporphyrin catalyst, Mn(TPFPP)Cl. This system displays high efficiency for α,β-desaturation of various cyclic amines and ethers. Mechanistic probes suggest that the desaturation reaction occurs via an initial α-C-H hydroxylation pathway, which serves to protect the product from overoxidation.

The synthesis of syn- and anti-2(S)-phthalimidomethyl-2,3,4,4a,7,7a-hexahydro-6-oxo-5H-pyrano-[2 ,3-b]pyrroles as rigid β-bend peptide-mimetics

-

SYNTHESIS OF BROMO-SUBSTITUTED BICYCLIC OXALACTAM AND UNUSUAL ANIONIC DESALTING OLIGOMERIZATION OF ITS SODIUM SALT

New bromo-substituted bicyclic oxalactam, 4(e)-bromo-8-oxa-6-azabicyclooctan-7-one (1) was synthesized from sodium 3,4-dihydro-2H-pyran-2-carboxylate.Sodium salt of 1 was found to be oligomerized with the simultaneous desalting in dimethylformamide at 25 degC to give novel oligomers having a bicyclic oxalactam ring in each monomer unit.