83575-64-8

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 100573-50-0 (E)-4-phenyl-2-(trimethylsiloxy)but-3-enenitrile 

Downstream Products

• 100573-02-2 4-Methyl-3-phenyl-pentanoic acid amide 
• 100573-01-1 2-Isopropyl-4-phenyl-2-(trimethylsiloxy)-3-butennitril 
• 62114-61-8 3-Phenyl-5-hexenamid 
• 100603-80-3 2-(2-Phenylethenyl)-2-(trimethylsiloxy)-4-pentennitril 
• 100573-06-6 4-Amino-4-oxo-2-phenylbutansaeure-ethylester 
• 100573-05-5 2-Cyan-4-phenyl-2-(trimethylsiloxy)-3-butensaeure-ethylester 
• 26860-44-6 3,4-Diphenylbutanamid 
• 100573-04-4 2-Benzyl-4-phenyl-2-(trimethylsiloxy)-3-butennitril 
• 91246-05-8 3-phenyl-pentanoic acid amide 
• 100573-00-0 2-Ethyl-4-phenyl-2-(trimethylsiloxy)-3-butennitril 
• 772-13-4 3-phenylbutanonamide 
• 108583-48-8 trans-4-Phenyl-2-methyl-2-trimethylsiloxy-3-butenenitrile 

Relevant academic research and scientific papers

Trimethylsilyl Cyanide - A Reagent for Umpolung, XI. On the Ambident Character of Substituted Allylic Anions.

The dependence of the α/γ-ratio of alkylation products on several factors has been determined with 1-cyano-3-aryl-1-(trimethylsiloxy)allylic anions.Increasing amounts of γ-product are found in more polar solvents, with larger alkali ions, on addition of HMPT, with smaller alkyl groups in the electrophile, and especially with p-cyanophenyl groups.In contrast, temperature and leaving groups have minor effects.On substitution of the O-silyl group by O-methyl and O-ethoxycarbonyl, α-alkylation predominates strongly.The results are compared to known allylic anions.Furthermore, the isomerisation of compounds of type C to type B is described as well as a new addition reaction of cyanoformates to aldehydes.