83600-07-1Relevant articles and documents
Organocatalytic enantioselective formal C(sp2)-H alkylation
Manna, Madhu Sudan,Mukherjee, Santanu
supporting information, p. 130 - 133 (2015/01/30)
An organocatalytic enantioselective formal C(sp2)-H alkylation is reported. This alkylative desymmetrization of prochiral 2,2-disubstituted cyclopentene-1,3-dione is catalyzed by a bifunctional tertiary aminourea derivative, utilizes air-stable and inexpensive nitroalkanes as the alkylating agents, and delivers synthetically versatile five-membered carbocycles containing an all-carbon quaternary stereogenic center remote from the reaction site in excellent enantioselectivity.
NITROEHYLENE: NITROETHYLATON OF AMINES
Ranganathan, D.,Ranganathan, S.,Bamezai, S.
, p. 2789 - 2792 (2007/10/02)
The nitroehylation of amines is demosntrated to be a general reaction for bases in the pKa range of 2 - 8 and that it proceeds through a key intra-molecular quenching step.The reaction, illustrated with aromatic amines, aliphatic amines and het