837365-03-4 Usage
General Description
(4,6-Dichloro-pyridin-2-yl)-hydrazine is a chemical compound with the molecular formula C5H5Cl2N3. It is a derivative of pyridine and hydrazine, and it is commonly used in the synthesis of pharmaceuticals and agrochemicals. (4,6-DICHLORO-PYRIDIN-2-YL)-HYDRAZINE is a versatile building block in organic synthesis, and it is used as a precursor in the production of various heterocyclic compounds. It has also been studied for its potential biological and pharmacological activities. However, it is important to handle this chemical with care as it may pose health hazards, and proper safety measures should be taken when working with it.
Check Digit Verification of cas no
The CAS Registry Mumber 837365-03-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,7,3,6 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 837365-03:
(8*8)+(7*3)+(6*7)+(5*3)+(4*6)+(3*5)+(2*0)+(1*3)=184
184 % 10 = 4
So 837365-03-4 is a valid CAS Registry Number.
837365-03-4Relevant articles and documents
Regiochemically flexible substitutions of di-, tri-, and tetrahalopyridines: The trialkylsilyl trick
Schlosser, Manfred,Bobbio, Carla,Rausis, Thierry
, p. 2494 - 2502 (2007/10/03)
(Chemical Equation Presented) 2,4-Difluoropyridine, 2,4-dichloropyridine, 2,4,6-trifluoropyridine, 2,4,6-trichloropyridine and 2,3,4,6-tetrafluoropyridine react with standard nucleophiles exclusively at the 4-position under halogen displacement. However, the regioselectivity can be completely reversed if a trialkylsilyl group is introduced in the 5-position of the 2,4-dihalopyridines or in the 3-position of the 2,4,6-trihalopyridines or 2,3,4,6-tetrahalopyridine. Then only the halogen most remote from the bulky silyl unit (at the 2-position in the case of the 2,4-halopyridines, at the 6-position with the other substrates) gets involved in the exchange process. After removal of the silyl protective group the nucleophile is invariably found to occupy the nitrogen-neighboring position.