59047-70-0

Usage

Uses

Used in Pharmaceutical Industry:
(2-Chloro-pyridin-4-yl)-dimethyl-amine is used as an intermediate in the synthesis of various pharmaceutical agents. Its unique structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (2-Chloro-pyridin-4-yl)-dimethyl-amine is employed in the production of pesticides and other agrochemical products. Its chemical properties make it a valuable asset in creating effective solutions for pest control and crop protection.
Used in Research and Development:
(2-Chloro-pyridin-4-yl)-dimethyl-amine may also have potential uses in research and development as a building block for the creation of new chemical compounds with diverse properties and applications. Its versatility in chemical reactions can lead to the discovery of innovative materials and substances for various industries.

Upstream product

• 1122-58-3 dmap 
• 26452-80-2 2,4-dichloropyridine 
• 124-40-3 dimethyl amine 
• 837365-00-1 2,4,6-trichloro-3-(trimethylsilyl)pyridine 
• 73583-37-6 2-chloro-4-bromopyridine 
• 506-59-2 N,N-dimethylammonium chloride 
• 837365-03-4 2,4-dichloro-6-hydrazinopyridine 
• 98027-84-0 2,6-dichloro-4-iodopyridine 
• 16063-69-7 2,4,6-trichloropyridine 
• 2402-78-0 2,6-dichloropyridine 

Downstream Products

• 1421748-75-5 C₂₇H₄₂N₄O₃S 
• 1421748-74-4 C₂₃H₃₈N₄O₃S 
• 1421748-73-3 C₂₃H₃₆N₄O₃S 
• 1421748-72-2 C₂₈H₄₃N₅O₄S 
• 1421748-71-1 C₂₂H₃₁N₅O₄S 
• 1421748-70-0 C₂₈H₄₄N₄O₂S 
• 1421748-69-7 C₂₂H₃₂N₄O₂S 
• 1421748-68-6 C₂₀H₂₈N₄O₂S 
• 1421748-67-5 C₁₄H₂₁F₃N₄O₂S 
• 1421748-66-4 C₁₄H₂₄N₄O₂S 
• 1416450-11-7 N²,N²'-((1R,2R)-cyclohexane-1,2-diyl)bis(N⁴,N⁴-dimethylpyridine-2,4-diamine) 
• 1421748-76-6 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-((4-(dimethylamino)pyridin-2-yl)amino)cyclohexyl)thiourea 
• 85698-56-2 N⁴,N⁴,N^4',N^4'-tetramethyl-[2,2'-bipyridine]-4,4'-diamine 
• 1290059-15-2 2-chloro-6-(cyclohex-2-en-1-yl)-N,N-dimethylpyridin-4-amine 

Relevant academic research and scientific papers

PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS

New pyrazolopyridmiin-2-yl derivatives are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Selective and multiple functionalization of pyridines and alkaloids via Mg- and Zn-organometallic intermediates

Chemical equations presented. Quinine, nicotine, and related electron-rich amino-substituted pyridines were readily metalated using LiCl-solubilized TMP (2,2,6,6-tetramethylpiperidyl) bases in the presence of BF3· OEt2. A full pyridi

DIARYLAMINE-SUBSTITUTED QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS

Novel diarylamine-substituted quinolone compounds and pharmaceutical compositions, certain of which have been found to inhibit inducible NOS synthase have been discovered, together with methods of synthesizing and using the compounds including methods for the treatment of iNOS-mediated diseases in a patient by administering the compounds.

Regiochemically flexible substitutions of di-, tri-, and tetrahalopyridines: The trialkylsilyl trick

(Chemical Equation Presented) 2,4-Difluoropyridine, 2,4-dichloropyridine, 2,4,6-trifluoropyridine, 2,4,6-trichloropyridine and 2,3,4,6-tetrafluoropyridine react with standard nucleophiles exclusively at the 4-position under halogen displacement. However, the regioselectivity can be completely reversed if a trialkylsilyl group is introduced in the 5-position of the 2,4-dihalopyridines or in the 3-position of the 2,4,6-trihalopyridines or 2,3,4,6-tetrahalopyridine. Then only the halogen most remote from the bulky silyl unit (at the 2-position in the case of the 2,4-halopyridines, at the 6-position with the other substrates) gets involved in the exchange process. After removal of the silyl protective group the nucleophile is invariably found to occupy the nitrogen-neighboring position.

First direct C-2-lithiation of 4-DMAP. Convenient access to reactive functional derivatives and ligands

The first direct α-lithiation of 4-DMAP has been peformed via reaction with the BuLi-Me2N(CH2)2-OLi (BuLi-LiDMAE) reagent. This new methodology avoids the use of a activation-lithiation-regeneration sequence or halogen-met