59047-70-0Relevant articles and documents
PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS
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Paragraph 76; 77; 78, (2015/06/25)
New pyrazolopyridmiin-2-yl derivatives are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).
DIARYLAMINE-SUBSTITUTED QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS
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Page/Page column 47, (2009/04/25)
Novel diarylamine-substituted quinolone compounds and pharmaceutical compositions, certain of which have been found to inhibit inducible NOS synthase have been discovered, together with methods of synthesizing and using the compounds including methods for the treatment of iNOS-mediated diseases in a patient by administering the compounds.
First direct C-2-lithiation of 4-DMAP. Convenient access to reactive functional derivatives and ligands
Cuperly, David,Gros, Philippe,Fort, Yves
, p. 238 - 241 (2007/10/03)
The first direct α-lithiation of 4-DMAP has been peformed via reaction with the BuLi-Me2N(CH2)2-OLi (BuLi-LiDMAE) reagent. This new methodology avoids the use of a activation-lithiation-regeneration sequence or halogen-met