83767-03-7Relevant academic research and scientific papers
Synthesis and hybridization properties of the conjugates of oligonucleotides and stabilization agents. Part 3
Sottofattori, Enzo,Anzaldi, Maria,Mazzei, Mauro,Miele, Mariangela,Balbi, Alessandro,Pyshnyi, Dmitri S.,Zakharova, Olga D.,Abramova, Tatyana V.
, p. 1515 - 1522 (2007/10/03)
New compounds having tri- or pentamethylenamine linker functions were synthesized. These derivatives were covalently attached through the 5′-phosphoramide linkage to heptanucleotide pd(CCAAACA). Complementary complexes of the octanucleotide pd(TGTTTGGC) a
PI-3 KINASE INHIBITOR PRODRUGS
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Page 59-64, (2010/02/09)
The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.
