83800-92-4

Basic information

• Product Name: 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
• CAS NO: 83800-92-4
• Molecular Weight: 258.707
• Mol File: 83800-92-4.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one(83800-92-4)
• EPA Substance Registry System: 2-(3-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one(83800-92-4)

Safety Data

• Hazardous Substances Data: 83800-92-4(Hazardous Substances Data)

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 28144-70-9 anthranilic acid amide 
• 118-48-9 isatoic anhydride 
• 1885-29-6 anthranilic acid nitrile 
• 108-41-8 1-chloro-3-methylbenzene 
• 70288-97-0 1-chloro-3-(dibromomethyl)benzene 
• 703-59-3 homophthalic anhydride 

Downstream Products

• 1448068-43-6 C₁₅H₁₀ClN₅ 
• 1448068-56-1 C₁₄H₁₁ClN₄ 
• 1252492-30-0 2-(3-chlorophenyl)-3H-quinazoline-4-thione 

Relevant articles and documents

A choline hydroxide catalyzed synthesis of 2,3-dihydroquinazolin-4(1: H)-ones in an aqueous medium

A simple, metal and ligand-free protocol for the synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives using choline hydroxide (ChOH) as an effective catalyst in an aqueous medium has been developed. The good to high yield of the desired product is obtained, with a low environmental factor and high atom economy. ChOH was found to be recyclable up to six consecutive runs without significant loss in its activity. The use of water as an environmentally benign solvent, ease of work up and efficient recyclability of the catalyst makes this process more advantageous and greener.

Efficient one-pot synthesis of 2,3-dihydroquinazoline-4(1H)-ones promoted by FeCl3/neutral Al2O3

2,3-Dihydroquinazolin-4(1H)-one derivatives have been synthesized via one-pot reaction of isatoic anhydride, aromatic aldehyde, and ammonium acetate catalyzed by FeCl3/neutral Al2O3 in tert-butanol under reflux conditions.

High acidity cellulose sulfuric acid from sulfur trioxide: A highly efficient catalyst for the one step synthesis of xanthene and dihydroquinazolinone derivatives

A cellulose sulfonate catalyst (HS-cellulose sulfonate) with high stability, excellent catalytic activity and high acidity value (about 1.55 mmol g-1) was successfully prepared by SO3 gas phase sulfonation. The basic morphology and nanostructure of the catalyst were determined by HRTEM, XRD, IR, TG, etc. In addition, the catalyst was applied to the catalytic reaction of a dihydroquinazolinone derivative and a xanthene compound, and very valuable results were obtained. The development and preparation of cellulose sulfonate catalysts provide a good approach for the development and application of cellulose, and also an important application of green organic catalytic synthesis methodology.