83806-75-1

Usage

Uses

Used in Pharmaceutical Industry:
(4-BROMOPHENYL)(5,7-DIBROMO-1-BENZOFURAN-2-YL)METHANONE is used as a compound with potential pharmacological applications due to its unique structural features, including the presence of bromine substitutions and a ketone functional group. These characteristics may contribute to its interaction with biological targets, making it a candidate for the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, (4-BROMOPHENYL)(5,7-DIBROMO-1-BENZOFURAN-2-YL)METHANONE may be utilized as a compound with potential biological activities. Its structural components could be harnessed to create novel agrochemicals, such as pesticides or herbicides, that target specific pests or weeds while minimizing harm to the environment and non-target organisms.

Upstream product

• 90-59-5 3,5-Dibromosalicylaldehyde 
• 99-73-0 para-bromophenacyl bromide 
• 99-90-1 para-bromoacetophenone 
• 110-86-1 pyridine 
• 110829-99-7 3.5.4'-tribromo-2-hydroxy-trans-chalcone 
• 7726-95-6 bromine 
• 86293-49-4 (E)-1-(4-bromophenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one 

Downstream Products

• 83806-76-2 (4-Bromo-phenyl)-(5,7-dibromo-benzofuran-2-yl)-methanol 

Relevant academic research and scientific papers

Mechanochemical solid-state synthesis of 2-aminothiazoles, quinoxalines and benzoylbenzofurans from ketones by one-pot sequential acid- and base-mediated reactions

α-Chloroketones-obtained by the atom-economical chlorination of ketones with trichloroisocyanuric acid (TCCA) in the presence of p-TSA under ball-milling conditions-were set up for a sequential base-mediated condensation reaction with thiourea/thiosemicarbazides, o-phenylenediamine and salicylaldehyde to afford 2-aminothiazoles, 2-hydrazinylthiazoles, quinoxalines and benzoylbenzofurans, respectively, in respectable yields. The viability of one-pot sequential acid- and base-mediated reactions in the solid state under ball-milling conditions is thus demonstrated.

Microwave-mediated solvent free Rap-Stoermer reaction for efficient synthesis of benzofurans

The Rap-Stoermer reaction of salicylaldehydes with diverse phenacyl bromide and phenacyl iodides proceeded cleanly to afford various functionalized benzofurans in excellent yields under base-mediated solvent free microwave irradiation conditions.

Reaction of chalcones with NBS, a simple one pot synthesis of 2-aroylbenzo[b]furanes

A simple one pot synthesis of 2-aroylbenzo[b]furanes has been achieved by bromomethoxylation with NBS and subsequent treatment of the appropriately substituted 2-hydroxychalcones with sodium hydroxide.