83814-52-2Relevant academic research and scientific papers
Plant Growth Regulators in Eucalyptus grandis. V Synthesis of the G-Regulators
Bolte, Matthew L.,Crow, Crow, Wilfrid D.,Yoshida, Shigeo
, p. 1421 - 1429 (2007/10/02)
Problems associated with earlier synthetic approaches to the G-regulators have been overcome by the use of the Mannich reaction in aprotic media.Under these conditions the Mannich base formed from the reaction of 1,3-diketones and aldehydes is stabilized by internal hydrogen bonding and can be isolated in high yield.In aqueous acid rapid elimination occurs to give the 2-methylene 1,3-diketones, which first enolize then add oxygen to generate the G-regulator structure.The steric limitations of the reactions are examined.
