83855-47-4

Basic information

• Product Name: CARBAMIC ACID, (2-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)PHENYL)-, ETHYL EST
• Synonyms: CARBAMIC ACID, (2-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)PHENYL)-, ETHYL EST
• CAS NO: 83855-47-4
• Molecular Formula: C₁₅H₂₄N₂O₄
• Molecular Weight: 296.36206
• Mol File: 83855-47-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 419.9°C at 760 mmHg
• Flash Point: 207.7°C
• Appearance: /
• Density: 1.144g/cm³
• Vapor Pressure: 8.42E-08mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: CARBAMIC ACID, (2-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)PHENYL)-, ETHYL EST(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAMIC ACID, (2-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)PHENYL)-, ETHYL EST(83855-47-4)
• EPA Substance Registry System: CARBAMIC ACID, (2-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)PHENYL)-, ETHYL EST(83855-47-4)

Safety Data

• Hazardous Substances Data: 83855-47-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H24N2O4/c1-4-20-15(19)17-13-7-5-6-8-14(13)21-10-12(18)9-16-11(2)3/h5-8,11-12,16,18H,4,9-10H2,1-3H3,(H,17,19)

Upstream product

• 95-55-6 2-amino-phenol 
• 56836-51-2 ethyl (2-hydroxyphenyl)carbamate 
• 52134-45-9 (2-Oxiranylmethoxy-phenyl)-carbamic acid ethyl ester 
• 75-31-0 isopropylamine 

Relevant articles and documents

Synthesis and structure-activity relationships of new β-adrenoreceptor antagonists. Evidence for the electrostatic requirements for β-adrenoreceptor antagonists

A series of mono- and disubstituted phenoxypropanolamines, structurally related to practolol and acebutolol, has been synthesized and tested for β-adrenoreceptor blocking activity. Structure-activity relationships are discussed. The reasons for the lack of activity of compounds 3n and 4n have also been examined. The results suggest that the negative electrostatic potential above the phenyl ring of phenoxypropanolamines is essential for binding activity and point to the presence of an electropositive residue in the β-adrenoreceptor binding site.