83863-74-5

Usage

Uses

Used in Pharmaceutical Research:
2-Carboxymethyl-1-methylpyrrole-3-carboxylic acid is used as a building block for the synthesis of pharmaceutical compounds due to its reactivity and ability to chelate metal ions, which is beneficial in the development of metal-based drugs.
Used in Coordination Chemistry:
In the field of coordination chemistry, 2-Carboxymethyl-1-methylpyrrole-3-carboxylic acid is used as a ligand for the formation of coordination complexes, leveraging its chelating properties to create new materials with unique properties.
Used in Material Science:
2-Carboxymethyl-1-methylpyrrole-3-carboxylic acid is utilized in the development of new materials, particularly those that require metal chelation for enhanced properties, such as in catalysis or sensing applications.
Used in Organic Synthesis:
As a key intermediate in organic synthesis, 2-Carboxymethyl-1-methylpyrrole-3-carboxylic acid is used to construct a variety of organic compounds, taking advantage of its unique structure and reactivity.

InChI:InChI=1/C8H9NO4/c1-9-3-2-5(8(12)13)6(9)4-7(10)11/h2-3H,4H2,1H3,(H,10,11)(H,12,13)

Upstream product

• 107-20-0 2-chloroethanal 
• 542-05-2 acetonedicarboxylic acid 
• 74-89-5 methylamine 

Downstream Products

• 871819-39-5 2-methoxycarbonylmethyl-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 94133-60-5 C₁₀H₁₃NO₄ 
• 51856-79-2 N-methyl-2-(methoxycarbonylmethyl)pyrrole 
• 33369-52-7 methyl 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetate 
• 26171-23-3 1-methyl-5-(p-toluoyl)pyrrole-2-acetic acid 
• 49669-45-6 ethyl (1-methyl-1H-pyrrol-2-yl)acetate 
• 925917-92-6 1-methyl-7-(4-morpholinylcarbonyl)-4-{3-[(trifluoromethyl)oxy]phenyl}-1H-pyrrolo[3,2-c]pyridine hydrochloride 
• 925917-91-5 3-chloro-N-[1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide hydrochloride 
• 925917-90-4 N-[(3-chlorophenyl)methyl]-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-amine hydrochloride 
• 925917-53-9 4-[(3-chlorophenyl)oxy]-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine hydrochloride 
• 925917-93-7 4-(3-chlorophenyl)-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine hydrochloride 
• 925979-46-0 1-methyl-7-(4-morpholinylcarbonyl)-4-{3-[(trifluoromethyl)oxy]phenyl}-1H-pyrrolo[3,2-c]pyridine 
• 925979-45-9 3-chloro-N-[1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide 
• 925979-44-8 N-[(3-chlorophenyl)methyl]-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-amine 

Relevant academic research and scientific papers

Synthetic method of non-steroidal antiinflammatory drug pain killing

The invention discloses a synthesis method of non-steroidal anti-inflammatory drug tolmetin. The methodcomprises the following steps: sequentially preparing a sulfuric acid-containing acetonedicarboxylic acid crude product, 2-(2-acetoxy)-1-methyl-1H-pyrrole-3-formic acid and 2-(2-alkyl acetate)-1-methyl-1H-pyrrole-3-formic acid by taking citric acid or citric acid monohydrate as a raw material; and carrying out decarboxylation, acylation, hydrolysis and acidification to obtain tolmetin. The synthetic method provided by the invention overcomes the defect that the existing tolmetin preparation process depends on N-methylpyrrole, and is a low-cost, low-pollution and high-yield synthetic method of non-steroidal anti-inflammatory drug tolmetin.

COMBINATION OF CB2 LIGAND AND PARACETAMOL

Combination of one or more CB2 modulators and paracetamol are useful of treating conditions which are mediated by the activity of CB2 receptors such as an immune disorder, an inflammatory disorder, pain, rheumatoid arthritis, multiple sclerosis, osteoarthritis, and osteoporosis.

PYRROLOPYRIDINE DERIVATIVES

The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.