84012-61-3

Basic information

• Product Name: 2-chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide
• Synonyms: 2-chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide
• CAS NO: 84012-61-3
• Molecular Formula: C₁₁H₁₃Cl₂NO
• Molecular Weight: 246.13302
• EINECS: 281-702-6
• Mol File: 84012-61-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 337.2°C at 760 mmHg
• Flash Point: 157.7°C
• Appearance: /
• Density: 1.244g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: 2-chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide(84012-61-3)
• EPA Substance Registry System: 2-chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide(84012-61-3)

Safety Data

• Hazardous Substances Data: 84012-61-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13Cl2NO/c1-8(2)14(11(15)7-12)10-5-3-9(13)4-6-10/h3-6,8H,7H2,1-2H3

Upstream product

• 106-47-8 4-chloro-aniline 
• 770-40-1 N-(4-chlorophenyl)-N-isopropylamine 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 64212-74-4 Dithiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-diethyl ester 
• 64249-01-0 anilofos 
• 64213-68-9 Isobutyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-isobutyl ester 
• 64213-66-7 Methyl-phosphonothioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-isobutyl ester 
• 65343-98-8 Propyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-ethyl ester 
• 65343-99-9 Ethyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-ethyl ester 
• 64213-67-8 Methyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-ethyl ester 
• 64213-65-6 Methyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O-methyl ester 
• 64249-02-1 Thiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-diethyl ester 
• 64212-75-5 Dithiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-dipropyl ester 

Relevant articles and documents

ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS

Disclosed herein are certain acetamido derivatives that are DNA Polymerase Theta (Polθ) inhibitors of Formula (I). Also, disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of Polθ such as cancer, including homologous recombination (HR) deficient cancers.