840454-59-3Relevant academic research and scientific papers
Enantioselective Ni-Al Bimetallic Catalyzed exo -Selective C-H Cyclization of Imidazoles with Alkenes
Wang, Yin-Xia,Qi, Shao-Long,Luan, Yu-Xin,Han, Xing-Wang,Wang, Shan,Chen, Hao,Ye, Mengchun
, p. 5360 - 5364 (2018/05/01)
A Ni-Al bimetallic catalyzed enantioselective C-H exo-selective cyclization of imidazoles with alkenes has been developed. A series of bi- or polycyclic imidazoles with β-stereocenter were obtained in up to 98% yield and >99% ee. The bifunctional SPO ligand-promoted bimetallic catalysis proved to be critical to this challenging stereocontrol.
