84066-68-2

Basic information

• Product Name: (3E)-1-(4-methoxyphenyl)-4-phenylbut-3-en-1-one
• Synonyms: (3E)-1-(4-methoxyphenyl)-4-phenylbut-3-en-1-one
• CAS NO: 84066-68-2
• Molecular Weight: 252.313
• Mol File: 84066-68-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (3E)-1-(4-methoxyphenyl)-4-phenylbut-3-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-1-(4-methoxyphenyl)-4-phenylbut-3-en-1-one(84066-68-2)
• EPA Substance Registry System: (3E)-1-(4-methoxyphenyl)-4-phenylbut-3-en-1-one(84066-68-2)

Safety Data

• Hazardous Substances Data: 84066-68-2(Hazardous Substances Data)

Upstream product

• 116156-19-5 (E)-1-methoxy-4-(4-phenylbutyl-3-en-1-yn-1-yl)benzene 
• 1608-03-3 (E)-but-1-en-3-yn-1-ylbenzene 
• 90766-67-9 1,1-dibromo-4-phenyl-1,3-butadiene 
• 14371-10-9 (E)-3-phenylpropenal 
• 536-74-3 phenylacetylene 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 54619-93-1 (4-methoxyphenyl)(2-phenylcyclopropyl)methanone 
• 84066-65-9 1,2-di-p-anisyl-2-hydroxy-5-phenyl-4-penten-1-one 
• 119-52-8 4,4'-dimethoxybenzoin 
• 1896-62-4 (E)-benzalacetone 
• 211996-14-4 acetic acid (E)-1-methylene-3-phenyl-allyl ester 
• 100573-50-0 (E)-4-phenyl-2-(trimethylsiloxy)but-3-enenitrile 
• 22422-16-8 (E)-1-bromo-4-phenylbut-3-en-2-one 
• 4392-24-9 Cinnamyl bromide 

Downstream Products

• 144774-54-9 (Z)-1-(4-methoxyphenyl)-4-phenylbut-2-ene-1,4-dione 
• 94540-81-5 2-(4-methoxyphenyl)-5-phenylfuran 
• 84066-59-1 exo-6-phenyl-3-p-anisyl-1,2-diazabicyclo<3.1.0>hex-2-ene 
• 84066-55-7 (E)-1-p-anisyl-4-phenyl-3-buten-1-one N-tosylhydrazone 

Relevant articles and documents

Regioselective Synthesis of 2-Acylbutadienes from β,γ-Unsaturated Ketones

2-Acylbuta-1,3-dienes have been synthesized regioselectively from aromatic and heteroaromatic β,γ-unsaturated ketones (readily accessible via base-catalyzed addition of ketones to acetylenes) and aldehydes. The reaction smoothly proceeds with piperidine (

Retrosynthetic Analysis of α-Alkenyl-β-Diketones: Regio-and Stereoselective Two-Step Synthesis of Highly Arylated Representatives from Acetylenes, Ketones, and Acyl Chlorides

Highly arylated α-alkenyl-β-diketones are synthesized via a two-step sequence consisting of (i) potassium tert-butoxide/DMSO-catalyzed (E)-stereoselective C-H functionalization of ketones with acetylenes followed by (ii) magnesium bromide etherate/DIPEA-soft enolization of the formed β,γ-unsaturated ketones and regioselective acylation with acyl chlorides. The method is compatible with a broad range of substrates and shown to be applicable as an intermediate stage in the construction of polyarylated heterocycles.

A sequential synthesis of substituted furans from aryl alkynes and ketones involving a cerium(IV) ammonium nitrate (CAN)-mediated oxidative cyclization

A convenient, two-step synthesis of substituted furans from readily available aryl alkynes and ketones is reported. The furan-forming oxidative cyclization is mediated by the combination of cerium(IV) ammonium nitrate and potassium bromide and can be carried out in an open flask.