54619-93-1Relevant articles and documents
Visible-light-induced triple catalysis for a ring-opening cyanation of cyclopropyl ketones
Liu, Jing,Liu, Xiao-Peng,Wu, Hong,Wei, Yi,Lu, Fu-Dong,Guo, Kai-Rui,Cheng, Ying,Xiao, Wen-Jing
supporting information, p. 11508 - 11511 (2020/10/12)
An unprecedented triple catalytic, general ring-opening cyanation reaction of cyclopropyl ketones for the construction of γ-cyanoketones is described. The key is to merge photoredox catalysis with Lewis acid catalysis and copper catalysis to enable the selective cleavage of the carbon-carbon bonds and the selective coupling of the generated radical and cyanide anion.