84073-89-2

Upstream product

• 56124-48-2 monomethyl 1,2,3,6-tetrahydrophthalate 
• 75-36-5 acetyl chloride 
• 93603-11-3 1-methyl hydrogen 1,2-cis-1,2-cyclohex-4-ene dicarboxylate 

Downstream Products

• 84073-88-1 2-Formyl-5-(2-methyl-[1,3]dithiolan-2-yl)-cyclohexanecarboxylic acid methyl ester 
• 85329-10-8 5-Acetyl-2-(1,4-dimethoxy-naphthalene-2-carbonyl)-cyclohexanecarboxylic acid methyl ester 
• 95375-39-6 (1R,2S)-4-(2-Methyl-[1,3]dithiolan-2-yl)-cyclohexane-1,2-dicarboxylic acid 2-methyl ester 
• 95375-40-9 cis-1-hydroxymethyl-2-methoxycarbonyl-4-(1'-ethylendithioethyl)-cyclohexane 
• 84073-88-1 cis-1-formyl-2-methoxycarbonyl-4-(1'-ethylendithioethyl)-cyclohexane 
• 85293-76-1 4-Acetyl-2-(1,4-dimethoxy-naphthalene-2-carbonyl)-cyclohexanecarboxylic acid methyl ester 
• 85382-54-3 cis-1-carboxy-2-methoxycarbonyl-4-acetylcyclohexane 

Relevant academic research and scientific papers

Regiospecific Total Synthesis of 6-Deoxyanthracyclines: 4-Demethoxy-6-deoxydaunorubicin

A regiospecific approach to 6-deoxyanthracyclinones, which has resulted in the synthesis of the novel anthracycline 4-demethoxy-6-deoxydaunorubicin, is reported.The construction of aglycone entails the coupling of the metalated 1,4-dimethoxynaphthalene with 2-carbomethoxy-4-acetylcyclohexanal.The new aldehyde was prepared from cis tetrahydrophthalic monoester via a regioselective acylation followed by conversion of the carboxylic group to a formyl group.The daunosaminyl glycoside showed on HeLa cells the same cytotoxicity as daunorubicin.