84089-73-6Relevant articles and documents
Anti-influenza virus compound as well as preparation method and application thereof
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Paragraph 0131; 0134; 0136, (2021/05/01)
The invention provides an anti-influenza virus pharmaceutical compound, and a preparation method and application thereof. The compound provided by the invention is a prodrug, has remarkably improved bioavailability and antiviral activity compared with a parent drug, is suitable for treating/prepaid influenza virus infection related diseases, has improved pharmacokinetic characteristics, and is particularly suitable for being developed into an oral preparation.
A 1 - iodo ethyl isopropyl carbon ester preparation method (by machine translation)
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Paragraph 0011; 0012, (2017/06/08)
The invention discloses cephalosporins antibiotics of cefpodoxime proxetil intermediate 1 - iodo ethyl isopropyl carbon ester preparation method, will 1 - chloro ethyl isopropyl carbonate is dissolved in ethyl acetate, adds the sodium iodide, TBAB, calcium chloride heating reflux reaction 3h to obtain the target product 1 - iodo ethyl isopropyl carbonate, sample gas-phase detection purity _aogtao_ 95%, the yield of the crude mole _aogtao_ 90%, without passing through the distillation can be directly used for the next step synthesis. The invention synthetic product high purity, high yield and does not require the high vacuum distillation can be directly synthesizing the next step, for large-scale production and cost of cefpodoxime proxetil control provides a guarantee. (by machine translation)
3,3-DISUBSTITUTED-1-HYDROXYTRIAZ-1-ENE 2-OXIDES AND WOUND-HEALING COMPOSITIONS USING THEM
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Paragraph 00129, (2015/08/03)
Esters, carbonates and imides of 3,3-disubstituted-1-hydroxytriaz-1-ene 2-oxides of the formula I are disclosed. The compounds release nitric oxide (NO) under physiologic conditions, and pharmaceutical compositions containing them are useful to aid in wound healing.