84092-46-6

Upstream product

• 6515-21-5 4-methoxymethoxy-benzaldehyde 
• 84092-45-5 2',4'-bis(methoxymethoxy)-5'-(3,3-dimethylallyl)-6'-hydroxyacetophenone 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 870-63-3 prenyl bromide 
• 27364-71-2 2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone 
• 65490-09-7 2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone 

Downstream Products

• 84092-47-7 5,7,4'-trimethoxymethoxy-8-(3,3-dimethylallyl)-flavanone 
• 1174035-58-5 (2Z)-4,6-bis(methoxymethoxy)-2-[4-(methoxymethoxy)benzylidene]-7-(3-methylbut-2-en-1-yl)-1-benzofuran-3(2H)-one 
• 112772-82-4 2,4,4',6-tetrahydroxy-3-(3,3-dimethylallyl)chalcone 
• 68682-02-0 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-(3-methyl-but-2-enyl)-chroman-4-one 

Relevant academic research and scientific papers

A one-pot synthesis of aurones from substituted acetophenones and benzaldehydes: A concise synthesis of aureusidin

A one-pot synthesis of aurones from substituted acetophenone and benzaldehyde has been developed on the basis of an improved Algar-Flynn-Oyamada reaction. By using this method, several aurones were prepared in three steps from commercial starting materials. The usefulness of this one-pot strategy was confirmed by a synthesis of aureusidin, an inhibitor of iodothyronine deiodinase, in 41% overall yield. In comparison with a two-step synthesis of this product from the same substrates, the one-pot strategy was more effective, giving a higher yield and requiring fewer and simpler operations. Georg Thieme Verlag Stuttgart New York.

Design, synthesis, and biological evaluation of prenylated chalcones as vasorelaxant agents

Five prenylated chalcones and one allylated chalcone were prepared according to the analysis based on support vector machine (SVM) classification model. Most of the synthesized chalcones showed potent vasorelaxant activities through evaluation in aortic r

Synthesis, biological evaluation of prenylflavonoids as vasorelaxant and neuroprotective agents

A series of prenylflavonoids with multiple hydroxyl groups were synthesized and evaluated for their vasorelaxant activities against rat aorta rings pre-contracted by phenylephrine (PE), as well as their neuroprotective effects against OGD induced PC12 cel

A New Synthesis of 4',5,7-Trihydroxy-8-(3,3-dimethylallyl)flavanone

The title prenylated flavanone (V) isolated from the roots of Marshallia grandiflora has been synthesised by a new route starting from 2-hydroxy-4,6-di-(methoxymethoxy) acetophenone (I).Prenylation of I gives 3-C-prenyl ke