841-01-0 Usage
General Description
(4-amino-2-methylpyrimidin-5-yl)methyl trihydrogen diphosphate is a chemical compound that is used in the synthesis of DNA and RNA. It is an essential component of nucleotide metabolism and is involved in the production of energy within cells. (4-amino-2-methylpyrimidin-5-yl)methyl trihydrogen diphosphate is also known as thiamine pyrophosphate and is a coenzyme in several biochemical reactions, particularly in the metabolism of carbohydrates. It plays a crucial role in the conversion of glucose into energy and is necessary for the proper functioning of the nervous system. Additionally, it is a vital component of thiamine, which is an essential nutrient for the human body.
Check Digit Verification of cas no
The CAS Registry Mumber 841-01-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,4 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 841-01:
(5*8)+(4*4)+(3*1)+(2*0)+(1*1)=60
60 % 10 = 0
So 841-01-0 is a valid CAS Registry Number.
841-01-0Relevant articles and documents
Thiamin phosphate synthase: The rate of pyrimidine carbocation formation
Hanes, Jeremiah W.,Ealick, Steven E.,Begley, Tadhg P.
, p. 4860 - 4861 (2007)
Thiamin phosphate synthase couples 4-amino-5-(hydroxymethyl)-2-methylpyrimidine pyrophosphate (HMP-PP) and 4-methyl-5-(β-hydroxyethyl)thiazole phosphate (Thz-P) to make thiamin phosphate on the biosynthetic route to thiamin-PP, the active form of vitamin B1. We show that this coupling reaction goes through a pyrimidine carbocation intermediate by using transient state kinetic methods, and that the rate constant for carbocation formation at the active site of the enzyme is 0.4 s-1. Copyright
