841-14-5Relevant academic research and scientific papers
A DFT and experimental study of the spectroscopic and hydrolytic degradation behaviour of some benzylideneanilines
Robertson, Tahjna I.,Nelson, Peter N.
, (2021/10/12)
The spectroscopic and hydrolytic degradation behaviour of some N-benzylideneanilines are investigated experimentally and theoretically via high quality density function theoretical (DFT) modelling techniques. Their absorption and vibrational spectra, accurately predicted by DFT calculations, are highly dependent on the nature of the substituents on the aromatic rings, hence, though some of their spectroscopic features are similar, energetic differences exist due to differences in their electronic structures. Whereas the o-hydroxy aniline derived adducts undergo hydrolysis via two pathways, the most energetically economical of which is initiated by a fast enthalpy driven hydration, over a conservative free energy (ΔG?) barrier of 53 kJ mol?1, prior to the rate limiting entropy controlled lysis step which occurs via a conservative barrier of ca.132 kJ mol?1, all other compounds hydrolyse via a slower two-step pathway, limited by the hydration step. Barriers heights for both pathways are controlled primarily by the structure and hence, stability of the transition states, all of which are cyclic for both pathways.
Copper(II) nitroaromatic Schiff base complexes: Synthesis, biological activity and their interaction with DNA and albumins
Martins, Darliane A.,Bomfim Filho, Lucius F.,Da Silva, Cleiton M.,De Fátima, ?ngelo,Louro, Sonia R. W.,Batista, Denise G. J.,Soeiro, Maria De Nazaré C.,De Carvalho, Jo?o Ernesto,Teixeira, Letícia R.
, p. 87 - 97 (2016/12/18)
Copper(II) complexes of the Schiff base ligands 2-((5-nitrofuran-2-yl)methyleneamino) phenol (HL1) and 2-(4-nitrobenzylideneamino)phenol (HL2) were prepared and characterized using physicochemical and spectroscopic techniques. In these complexes the Schif
Catalyst-free allylation of 2-aminophenol–derived aldimines with allyltrichlorosilane under thermal conditions
Venkatanna, Kesa,Ramanathan, Chinnasamy Ramaraj
supporting information, p. 3650 - 3653 (2017/08/22)
Allylation of 2-aminophenol-derived aldimines using allyltrichlorosilane under catalyst free conditions has been developed. This reaction afforded the corresponding homoallylic amines in good to excellent yields (68–94%). The salicylaldehyde-derived aldimines as well as benzoylhydrazone also found to react with allyltrichlorosilane smoothly under the same conditions, to furnish the corresponding homoallylic amine derivatives. This study suggests that the phenolic –OH group acts as an anchoring group for the transfer of allyl group from allyl silane reagent.
Abnormal effect of hydroxyl on the longest wavelength maximum in ultraviolet absorption spectra for bis-aryl Schiff bases
Cao, Chao-Tun,Zhou, Wei,Cao, Chenzhong
, (2017/09/19)
Two sets of bis-aryl Schiff bases that contain 4(or 4′)-OH and 2(or 2′)-OH were synthesized. The first set consists of 4-HOArCH=NArY and XArCH=NArOH-4′, and the second set consists of 2-HOArCH=NArY and XArCH=NArOH-2′. Their ultraviolet absorption spectra were measured and investigated. A very interesting phenomenon was observed by analyzing their wave number νmax (cm?1) of longest wavelength maximum λmax (nm) of ultraviolet. Compared with the change regularity of the νmax of XArCH=NArY (where the X and Y excluded OH), the 4′-position hydroxyl (4′-OH) and 2′-position hydroxyl (2′-OH) have abnormal performance. The details are the following: the 4′-OH contributes an additional red shift to the νmax of XArCH=NArOH-4′ (λmax increase), whereas the 2′-OH contributes an additional blue shift to the νmax of XArCH=NArOH-2′ (λmax decrease). In addition, there are ortho steric effects of all 2-OH and 2′-OH on the νmax for 2-HOArCH=NArY and XArCH=NArOH-2′, and the ortho steric effect contributes a red shift to their νmax. These experimental facts can provide an important theoretical reference for us using aryl Schiff base compounds as optical materials and performing the molecular design.
P-nitrobenzaldehyde Schiff base derivative as well as preparation method and application thereof
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Paragraph 0026; 0027; 0028; 0029; 0031; 0032; 0033-0038, (2017/08/29)
The invention discloses a p-nitrobenzaldehyde Schiff base derivative as well as a preparation method and an application thereof. The p-nitrobenzaldehyde Schiff base derivative has a structural formula shown in the specification. During preparation, a cert
Synthesis and biological activities of 2-aminophenol-based Schiff bases and their structure-activity relationship
Aslam, Muhammad,Anis, Itrat,Mehmood, Rashad,Iqbal, Lubna,Iqbal, Samina,Khan, Inamullah,Chishti, Muhammad Salman,Perveen, Shagufta
, p. 109 - 115 (2016/01/25)
Six Schiff bases 8-13 were synthesized by condensation of 2-aminophenol (1) with various chloro- and nitro-benzaldehydes (2-7), characterized, and evaluated for antioxidant, antibacterial, lipoxygenase, and urease inhibitory potentials. All Schiff bases e
Photoprotective activity of resveratrol analogues
Polonini, Hudson Caetano,Lima, Larissa Lavorato,Goncalves, Karla Mara,Do Carmo, Antonio Marcio Resende,Da Silva, Adilson David,Raposo, Nadia Rezende Barbosa
, p. 964 - 968 (2013/04/10)
Resveratrol is a promising agent for protecting human skin from UV radiation and to reduce the occurrence of cutaneous malignancies. We describe the photoprotective activity of six resveratrol analogues using the diffuse transmittance technique to determine the SPF and the protection against UVA radiation. The analogues presented a varied profile of photoprotection, the SPF ranging from 2 to 10 and the UVAPF from 0 to 9. Among the six compounds tested, the protection against UVB sunrays provided by compound B was more significant than the protection provided by resveratrol; compounds C, D, E and F show photoprotection similar to resveratrol.
Features of the reactions of β-Aryl(heteryl)-α-nitroacrylates with N,N-, N,O-, and N,S-Binucleophiles
Baichurina,Baichurin,Filippenko,Aboskalova,Berestovitskaya
, p. 1400 - 1408 (2013/01/15)
The reactions of β-aryl(heteryl)-α-nitroacrylates with N,N-, N,O-, and N,S-binucleophiles proceed regiospecifically through the initial formation of the AdN products, among which only the product from oaminothiophenol was isolated. The conditions of converting the S-adducts into 2-aryl(heteryl)benzothiazole were found. The N-adducts formed in the reaction with hydrazine, o-phenylenediamine, and o-aminophenol undergo immediately the spontaneous transformation into the linear (azine, azomethine) or heterocyclic (benzimidazole) structures. Pleiades Publishing, Ltd., 2012.
Ni nanoparticles: Mild and efficient catalyst for the chemoselective synthesis of 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines
Khurana, Jitender M.,Sneha,Vij, Kanika
experimental part, p. 2606 - 2616 (2012/08/08)
(Chemical Equation Presented) A new and efficient method has been developed for the synthesis of biologically significant 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines using recyclable and inexpensive polyvinyl pyrrolidone (PVP)-stabilized Ni nanoparticles in ethylene glycol at room temperature in excellent yields. Copyright Taylor & Francis Group, LLC.
An efficient synthesis of 2-substituted benzoxazoles using cerium(III) chloride/sodium iodide as catalyst
Zhu, Xun,Wei, Yunyang
, p. 211 - 214 (2013/01/16)
An efficient and environmentally benign method for the synthesis of 2-substituted benzoxazoles is reported. The condensation of 2-aminophenol with an aldehyde gave an imine intermediate, which was cyclized and dehydrogenated to 2-substituted benzoxazole with good yield in the presence of CeCl 3 /NaI as catalyst. The one-pot synthesis was carried out in toluene at 100 ° C using O 2 as the oxidant.
