84132-56-9Relevant academic research and scientific papers
Four-Step One-Pot Catalytic Asymmetric Synthesis of Polysubstituted Tricyclic Compounds: Lipase-Catalyzed Dynamic Kinetic Resolution Followed by an Intramolecular Diels-Alder Reaction
Tsuchimochi, Izuru,Hori, Shuhei,Takeuchi, Yasuo,Egi, Masahiro,Satoh, Tomo-O,Kanomata, Kyohei,Ikawa, Takashi,Akai, Shuji
, p. 822 - 828 (2021)
Starting from readily available tertiary alcohols, four different reactions (a 1,3-migration of a hydroxy group, kinetic resolution, racemization, and an intramolecular Diels-Alder reaction) took place under co-catalysis by lipase and oxovanadium compounds in a one-pot process to produce polysubstituted tricyclic carbon frameworks in high yields and with high enantioselectivities. The key to the success of this process was the discovery that a silyl group attached to the terminal carbon of the vinyl moiety completely controls the direction of hydroxy group migration.
Silicon-Substituted Dienes in the Intramolecular Diels-Alder Reaction: Nagilactone Model Studies
Burke, Steven D.,Smith Strickland, Sharon M.,Powner, Tory H.
, p. 454 - 459 (2007/10/02)
The syntheses of 1-(2-propenoxy)-3-cyclohex-2-ene (6a), 1-(2-methyl-2-propenoxy)-3-cyclohex-2-ene (7a), 1-(3-methyl-2-butenoxy)-3-cyclohex-2-ene (8a), and the 5,5
