84141-83-3

Upstream product

• 121910-87-0 2-bromobenzo[b][1,4]dioxine 
• 187844-34-4 2-phenyl-2,3-dihydro-1,4-benzodioxin-2-carbonitrile 
• 98-80-6 phenylboronic acid 
• 5770-58-1 2-phenylbenzo[b][1,4]dioxine 
• 5770-68-3 2-hydroxy-2,3-dihydro-2-phenyl-1,4-benzodioxin 
• 187844-46-8 2-phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxylic acid ethyl ester 
• 121451-74-9 Toluene-4-sulfonic acid 2-phenyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl ester 

Downstream Products

• 187844-34-4 2-phenyl-2,3-dihydro-1,4-benzodioxin-2-carbonitrile 
• 84141-84-4 RX 811010 

Relevant academic research and scientific papers

Convenient synthesis of 2,2-disubstituted-2,3-dihydro-1,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-1,4-benzodioxins

Convenient syntheses of relatively rare 2,2-disubstituted-2,3-dihydro-1,4-benzodioxins from 2-substituted-2-hydroxy-2,3-dihydro-1,4-benzodioxins, as key synthetic intermediates, are reported. These new synthetic approaches require Lewis acid BF3-Et2O mediated nucleophilic substitution reaction or cyclization of suitable hydroxyphenols.

On the Reaction of α-(2-Hydroxyphenoxy)alkylketones with Dimethylsulphoxonium Methylide. A Novel Route to 2-Substituted-2,3-dihydro-2-hydroxymethyl-1,4-benzodioxins

A new route to 2-substituted-2,3-dihydro-2-hydroxymethyl-1,4-benzodioxins 3 based on the reaction of α-(2-hydroxyphenoxy)alkylketones 1 with dimethylsulphoxonium methylide in dimethylsulphoxide is reported.Besides the desired compounds 3, the isomeric 2H-