84186-29-8

Upstream product

• 110-89-4 piperidine 
• 52414-97-8 1-bromo-3-methyl-2-nitro-benzene 
• 570-24-1 2-Methyl-6-nitroaniline 
• 602-01-7 1-methyl-2,3-dinitrobenzene 

Downstream Products

• 84186-31-2 6-methyl-2-piperidinoaniline 
• 1057292-55-3 3-(2-nitro-3-piperidin-1-yl-phenyl)-2-oxo-propionic acid ethyl ester 
• 1057292-51-9 3-(2-nitro-3-piperidin-1-yl-phenyl)-2,5-dioxo-hexanedioic acid diethyl ester 
• 84186-33-4 6-methyl-1,2,3,4-tetrahydropyrido<1,2-a>benzimidazole 

Relevant academic research and scientific papers

C-FMS KINASE INHIBITORS

The invention is directed to compounds of Formula II: wherein A, R1, R2, R3, R4, X, Y and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.

C-FMS KINASE INHIBITORS

The invention is directed to compounds of formulae (I), (II) and (III), wherein A, R1, R2, R3, R4, X, Y and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein t

SUBSTITUTION OF NITRO GROUPS IN 2,3-DINITROTOLUENE

The reaction of 2,3-dinitrotoluene with piperidine gives a mixture of 2-piperidino-3-nitrotoluene and 3-piperidino-2-nitrotoluene in a ratio of 3:7.