84199-98-4

Basic information

• Product Name: METHYL 3-(3-PYRIDYL)PROPIONATE
• Synonyms: METHYL 3-(3-PYRIDYL)PROPIONATE;3-(3-Pyridyl)propionic acid methyl ester;Methyl 3-pyridin-3-ylpropanoate
• CAS NO: 84199-98-4
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 84199-98-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 134°C 12mm
• Flash Point: 134°C/12mm
• Appearance: /
• Density: 1.086 g/cm³
• Vapor Pressure: 0.0184mmHg at 25°C
• Refractive Index: 1.5010
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 132852
• CAS DataBase Reference: METHYL 3-(3-PYRIDYL)PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-(3-PYRIDYL)PROPIONATE(84199-98-4)
• EPA Substance Registry System: METHYL 3-(3-PYRIDYL)PROPIONATE(84199-98-4)

Safety Data

• Statements: 36/38
• Safety Statements: 26-36
• Hazardous Substances Data: 84199-98-4(Hazardous Substances Data)

Usage

General Description

Methyl 3-(3-pyridyl)propionate is a chemical compound that belongs to the class of organic compounds known as pyridine carboxylic acids. It is specifically a pyridine carboxylic acid derivative and a methyl ester. METHYL 3-(3-PYRIDYL)PROPIONATE is used in the production of various pharmaceuticals and insecticides. It is known for its fruity odor and is commonly used as a flavoring agent in the food and beverage industry. Additionally, it has been studied for its potential pharmacological properties, including its ability to act as an antifungal and antibacterial agent.

InChI:InChI=1/C9H11NO2/c1-12-9(11)5-4-8-3-2-6-10-7-8/h2-3,6-7H,4-5H2,1H3

Upstream product

• 67-56-1 methanol 
• 3724-19-4 3-pyridine propionic acid 
• 626-55-1 3-Bromopyridine 
• 292638-85-8 acrylic acid methyl ester 
• 6163-58-2 tris-(o-tolyl)phosphine 
• 75-05-8 acetonitrile 
• 19337-97-4 trans-3-(3-pyridyl)acrylic acid 
• 81124-48-3 methyl (E)-3-(3-pyridyl)acrylate 

Downstream Products

• 104642-48-0 C₉H₁₂N₂O₂*C₉H₁₂O₃S 
• 1026169-28-7 3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-3-hydroxy-2-pyridin-3-ylmethyl-propionic acid methyl ester 
• 2859-67-8 3-(3-pyridyl)propan-1-ol 
• 200867-83-0 N-[4-(1-diphenylmethyl-piperidin-4-yl)-butyl]-3-(pyridin-3-yl)-propionamide 
• 320608-52-4 C₈H₁₁N₃O 
• 279253-44-0 methyl 3-(1-(2-chloro-4-(1-pentyloxy)benzyl)-2-methylimidazol-5-yl)-3-hydroxy-2-(3-pyridylmethyl)propanate 
• 6293-56-7 3-pyridinylethanol 
• 1028285-62-2 (E)-3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-pyridin-3-ylmethyl-acrylic acid methyl ester 
• 143564-59-4 (E)-3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-pyridin-3-ylmethyl-acrylic acid 
• 109839-74-9 3-(3-bromopropyl)pyridine 
• 69603-49-2 3-(pyridin-3'-yl)propanethiol 
• 944997-60-8 α-cyclohexyl-N-[1-[1-oxo-3-(3-pyridinyl)propyl]-4-piperidinyl]benzeneacetamide 
• 3724-19-4 3-pyridine propionic acid 
• 84199-99-5 3-(3-Pyridyl)propionsaeureamid 

Relevant articles and documents

MICROBIOCIDAL QUINOLINE DIHYDRO-(THIAZINE)OXAZINE DERIVATIVES

Compounds of the formula (I): Formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.

An investigation into the one-pot Heck olefination-hydrogenation reaction

Herein is described an operationally simple process concerning the observation that, following either inter-, or intramolecular Heck olefination, stirring of the so formed substituted alkenyl product under an atmosphere of hydrogen efficiently effects alkene hydrogenation. Overall this two-operation, one-pot "reductive Heck" sequence is notable since direct reductive Heck processes, using additives such as formate salts, are restricted to a limited range of substrates. In total 25 examples are reported (yields ranging from 0 to 95%), which were selected in order to probe the scope and limitations of this method. Finally, the utility of this sequence was demonstrated in a short synthesis of the calcimimetic agent, cinacalcet.

Heterocyclic compounds as P2X7 ion channel blockers

The present invention relates to a novel series of 4,5-diphenyl-2-amino-4,5-dihydro-imidazole derivatives of the formula II: 1 wherein R, R1, R2, R3, R4, R5, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are P2X7 ion channel blockers and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases having an inflammatory component, including inflammatory bowel disease, rheumatoid arthritis and disease conditions associated with the central nervous system, such as stroke, Alzheimer''s disease, etc.