842149-91-1

Upstream product

• 57260-73-8 N-BOC-1,2-diaminoethane 
• 530-62-1 1,1'-carbonyldiimidazole 
• 396091-74-0 H-Phe-(2S,4R)-(4-OCO-NH-CH₂-CH₂-NH-Boc)-Pro-Phg-D-Trp(Boc)-Lys(Boc)-Tyr(Bzl)-OH 

Downstream Products

• 396091-73-9 pasireotide 

Relevant academic research and scientific papers

NOVEL PROCESS FOR THE PREPARATION OF PASIREOTIDE

The present invention relates to a novel process for the preparation of Pasireotide of formula 11 [Cyclo [Phe-{4-(OCO-NH-CH2-CH2-NH2)) Pro}-Phg-DTrp-Lys-Tyr(Bzl)]]. The invention also relates to a novel intermediate compound of formula 8 and process thereof which is used for preparation of compound of formula 11.

A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential

A rational drug design approach, capitalizing on structure-activity relationships and involving transposition of functional groups from somatotropin release inhibitory factor (SRIF) into a reduced size cyclohexapeptide template, has led to the discovery o