842167-63-9

Basic information

• Product Name: Benzene, 1-bromo-4-methoxy-2-[(phenylmethoxy)methyl]-
• CAS NO: 842167-63-9
• Molecular Formula: C15H15BrO2
• Molecular Weight: 307.187
• Mol File: 842167-63-9.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-methoxy-2-[(phenylmethoxy)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-methoxy-2-[(phenylmethoxy)methyl]-(842167-63-9)
• EPA Substance Registry System: Benzene, 1-bromo-4-methoxy-2-[(phenylmethoxy)methyl]-(842167-63-9)

Safety Data

• Hazardous Substances Data: 842167-63-9(Hazardous Substances Data)

Upstream product

• 19614-12-1 2-bromo-5-methoxybenzyl bromide 
• 100-51-6 benzyl alcohol 
• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 150192-39-5 2-Bromo-5-methoxybenzyl alcohol 
• 100-39-0 benzyl bromide 

Downstream Products

• 842167-45-7 1-[(benzyloxy)methyl]-2-ethenyl-5-methoxybenzene 
• 842167-65-1 2-[(benzyloxy)methyl]-4-methoxybenzaldehyde 

Relevant articles and documents

Divergent Access to Seven/Five-Membered Rings Based on [1,6]-Hydride Shift/Cyclization Process

We have achieved a divergent access to seven/five-membered rings based on a [1,6]-hydride shift/cyclization process from benzylidenemalonate with an o-alkoxymethyl group. Whereas Yb(OTf)3 afforded benzoxepines (with a seven-membered ring) selectively, indanes (with a five-membered ring) were the main products when Sc(OTf)3 was employed.

Copper-catalyzed allylations of zirconocene intermediates generated from o-alkenyl or o-alkynylbenzyl ether derivatives and zirconocene-butene complex

(Chemical Equation Presented) o-Alkenyl or alkynyl benzylzirconocene intermediate, which was readily generated by the reaction of 2-alkoxymethyl-styrene or 2-alkoxymethyl-1-(trimethylsilylethynyl)-benzene derivative with zirconocene-butene complex (Negishi reagent, "Cp 2Zr"), reacted with allyl or propargyl halides in the presence of a catalytic amount of CuCl to give allylation or allenylation products. Conversion to Dane's diene, which is a key intermediate for estrone synthesis, was efficiently carried out by enyne olefin metathesis of the allylation products.