84225-94-5Relevant articles and documents
An improved synthesis of PET dopamine D2 receptors radioligand [11c]raclopride
Fei, Xiangshu,Mock, Bruce H.,DeGrado, Timothy R.,Wang, Ji-Quari,Glick-Wilson, Barbara E.,Sullivan, Michael L.,Hutchins, Gary D.,Zheng, Qi-Huang
, p. 1897 - 1907 (2007/10/03)
An improved synthesis of [11C]raclopride is reported. The precursor desmethyl-raclopride was synthesized from 3,5-dichloro-2,6-dimethoxybenzoic acid and (S)-(-)-2-aminoethyl-1-ethylpyrrolidine via a straight-forward, four-step synthetic approac
Precursor synthesis and radiolabelling of the dopamine D2 receptor ligand [11C]raclopride from [11C]methyl triflate
Langer, Oliver,Nagren, Kjell,Dolle, Frederic,Lundkvist, Camilla,Sandell, Johan,Swahn, Carl-Gunnar,Vaufrey, Francoise,Crouzel, Christian,Maziere, Bernard,Halldin, Christer
, p. 1183 - 1193 (2007/10/03)
Desmethyl-raclopride was synthsized via a straightforward, three-step synthetic approach and used for the preparation of [11C]raclopride from [11C]methyl triflate. Conditions for the radiolabelling were optimized to obtain a simple a