84282-75-7

Upstream product

• 84282-66-6 C₁₄H₂₁N₃O₃ 
• 62-53-3 aniline 
• 100-63-0 phenylhydrazine 
• 3711-77-1 5-ethoxy-3-phenyl-1,3,4-oxadiazolin-2(3H)-one 
• 75-44-5 phosgene 
• 90437-32-4 2-ethoxycarbonylphenylhydrazine 
• 6233-02-9 ethyl phenylhydrazocarboxylate 

Downstream Products

• 111669-88-6 1-phenyl-3,3-diethyl-1-nitrosourea 

Relevant academic research and scientific papers

AN EFFICIENT METHOD FOR THE CONVERSION OF ARYLHYDRAZINES INTO 2-ARYL-4,4-DIALKYLSEMICARBAZIDES

Arylhydrazines are converted into 2-aryl-4,4-dialkylsemicarbazides by subsequent reaction with chloroformate, phosgene, dialkylamine, and alkaline hydrolysis.

Preparation of 2-phenylsemicarbazides

2-Phenylsemicarbazides are prepared by a multi-step process involving: (a) treating a phenylhydrazine, or salt thereof, with a chloroformate; (b) adding phosgene; (c) treating the resulting product with an amine; and (d) hydrolyzing the resulting acylated semicarbazide. The reaction can proceed through a Δ2 -1,3,4-oxadiazolin-5-one intermediate formed with heating in step (b). Certain of the products are novel compounds.